secondary bile acids biosynthesiswhole genomes sequencingObjective The gut microbiota affect liver metabolism and health through its metabolites. We previously observed that the microbiome may have a negative effect on non-alcoholic fatty liver disease (NAFLD) through elevated secondary bile acids (BAs) ...
(Lipid metabolism pathway)内的差异基因,次级胆汁酸代谢途径(Secondary bile acid biosynthesis pathway)的显著排名,根据上述结果,明确肠道微生物调控的次级胆汁酸代谢... 王旭 - 《南京中医药大学》 被引量: 0发表: 2024年 肠道菌群失调与胆汁酸代谢紊乱在结肠炎相关肠癌中的作用 目的结直肠癌(colorectal cancer,CRC...
Zhao C., Loefstedt C. and Wang X.: Sex pheromone biosynthesis in the Asian corn borer Ostrinia fumacalis (II): Biosynthesis of (E)- and (Z)-12-tetradecenyl acetate involves 14-desaturation. Arch. Insect Biochem. Physiol. 15: 57–65 (1990) CASGoogle Scholar Ziegler I.: Pterins: Pigm...
Genomic island TnSmu2 of Streptococcus mutans harbors a nonribosomal peptide synthetase-polyketide synthase gene cluster responsible for the biosynthesis of pigments involved in oxygen and H2O2 tolerance. Appl. Environ. Microbiol. 76, 5815–5826 (2010). Article CAS PubMed PubMed Central Google Scholar...
Leipold D, Wünsch G, Schmidt M et al (2010) Biosynthesis of ursolic acid derivatives by microbial metabolism of ursolic acid with Nocardia sp. strains – proposal of new biosynthetic pathways. Process Biochem 45:1043–1051. https://doi.org/10.1016/j.procbio.2010.03.013 Article CAS Google Sch...
Lichens and spore-derived cultured mycobionts of Teloschistes chrysophthalmus and Ramalina celastri were studied chemically, and results indicated that they produced, respectively, parietin and usnic acid as major secondary metabolites, which were purified and identified. Identification of the compounds...
Bile acidGerm-free miceA growing body of evidence has linked the gut microbiota to liver metabolism. The manipulation of intestinal microflora has been considered as a promising avenue to promote liver health. However, the effects ofLactobacillus gasseriLA39, a potential probiotic, on liver ...
A classic example for host-gut microbial co-metabolism is host biosynthesis of primary bile acids and their subsequent deconjugation and transformation by the gut microbiome. To understand these system-level host-microbe interactions, a mechanistic, multi-scale computational systems biology approach that ...
β-Lactam biosynthesisPeroxinsMycotoxinsBile acid metabolismPeroxisomes are eukaryotic organelles surrounded by a single bilayer membrane, containing a variety of proteins depending on the organism; they mainly perform degradation reactions of toxic metabolites (detoxification), catabolism of linear and ...
Molecular insights into the biosynthesis of guadinomine: A type III secretion system inhibitor. J. Am. Chem. Soc. 2012, 134, 17797–17806. [CrossRef] [PubMed] 22. Meier-Kolthoff, J.P.; Göker, M.; Spröer, C.; Klenk, H.P. When should a DDH experiment be mandatory in i...