I. (2017) Beta-lactamase database (BLDB) - structure and function. Journal of Enzyme Inhibition and Medicinal Chemistry, 32(1): 917-919.Naas T, Oueslati S, Bonnin RA, Dabos ML, Zavala A, Dortet L, Retailleau P, Iorga BI. Beta-lactamase database (BLDB) - structure and function. ...
Phylogenetic analysis. Amino acid sequences of 17 class A β-lactamases were retrieved from the Beta- Lactamase DataBase (BLDB, http://bldb.eu/), and were utilized for the phylogenetic analysis. Sequences were aligned using the program Clustal W31. A maximum-likelihood tree ...
Sequences were searched against the Comprehensive Antibiotic Resistance Database (CARD) and the GenBank (BLASTn) database to confirm the presence of one of the six target ESBL or carbapenemase genes. SHV and TEM bwvanaeertdraiea-bnlclaaltcosTtsEiaeMdmleygnaeistnneisfeipgseee1d8nc.tbeLesyda, ...
BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S. aureus Newman for susceptibility to cathelicidin antimicrobial peptide, we discovered BlaI as a novel cathelicidin resistance factor. Additionally, ...
ESCHERICHIA coliURINARY tract infectionsMOBILE genetic elementsDAIRY cattleAntimicrobial resistance (AMR) poses an imminent threat to global public health, driven in part by the widespread use of antimicrobials in both humans and animals. Within the dairy cattle industry, Gram-neg...
blaCTX-M-15ESBLEscherichia coliPhylogenetic groupAim: Escherichia coli (E. coli) producing extended-spectrum 桅-lactamase (ESBL) has become prevalent in worldwide. The ESBL-producing E. coli is genetically various, and isolates have been divided into four phylog-groups (A, Bl, B2 and D). ...
Blaak H, Lynch G, Italiaander R, Hamidjaja RA, Schets FM, de Roda Husman AM. Multidrug-resistant and extended spectrum beta-lactamase-producing Escherichia coli in Dutch surface water and wastewater. PLoS One. 2015; 10 (6):e0127752. doi: 10.1371/journal.pone.0127752. [ Cross Ref ]...
Beta-Lactamase Database (BLDB)-Structure and Function. J. Enzym. Inhib. Med. Chem. 2017, 32, 917–919. [Google Scholar] [CrossRef] BLAST: Basic Local Alignment Search Tool. Available online: https://blast.ncbi.nlm.nih.gov/Blast.cgi (accessed on 26 July 2022). The Comprehensive ...
susceptibility test was performed for ESBL-producing isolates against 12 clinically relevant antibiotics using the Kirby–Bauer disk diffusion susceptibility test. A phylogenetic tree was constructed for the sequence data obtained in this study and comparative sequence data obtained from GenBank. The ...