Beta-Lactamase Database (BLDB) is a comprehensive, manually curated public resource providing up-to-date structural and functional information focused on this superfamily of enzymes with a great impact on antibiotic resistance. All the enzymes reported and characterised in the literature are presented ...
File for generating beta lactamase databaseSandra, Wingaard Thrane
Phylogenetic analysis. Amino acid sequences of 17 class A β-lactamases were retrieved from the Beta- Lactamase DataBase (BLDB, http://bldb.eu/), and were utilized for the phylogenetic analysis. Sequences were aligned using the program Clustal W31. A maximum-likelihood tree ...
beta-lactamases are the most widespread resistance mechanisms to beta-lactam antibiotics, and there is a pressing need for novel, non-beta-lactam drugs. A database of over 200,000 compounds was docked to the active site of AmpC beta-lactamase to identify potential inhibitors. Fifty-six compound...
Sequences were searched against the Comprehensive Antibiotic Resistance Database (CARD) and the GenBank (BLASTn) database to confirm the presence of one of the six target ESBL or carbapenemase genes. SHV and TEM bwvanaeertdraiea-bnlclaaltcosTtsEiaeMdmleygnaeistnneisfeipgseee1d8nc.tbeLesyda, ...
... A Lethaby,RO Ayeleke,H Roberts - 《Cohrane Database of Systematic Reviews》 被引量: 164发表: 2016年 A prospective randomized study with mineral oil and oral lavage solution for treatment of faecal impaction in children SUMMARY Faecal impaction with or without encopresis is a very common...
Data on all patients ≥18 years discharged from three New York City hospitals within a single network were obtained retrospectively from a larger electronic database as part of an NIH-funded study (Distribution of the Costs of Antimicrobial Resistant Infections, NR010822). The study was approved ...
To identify novel MBLs inhibitors, starting from the available NDM-1 crystal structures [PDB code 3q6x and 3spu], a structure-based virtual screening (SBVS) of a large database of available chemicals was conducted, searching for potential inhibitors able to highly complement NDM-1 binding site...
protein sequence database, our sequence database of giant virus genomes, and previously described draft genome sequences from 14 Acanthamoeba species37; a set of previously described MBL fold proteins21; and a set of sequences from the UniProtKB database1 previously used for phylogeny ...
Database UniProtKB/Swiss-Prot: P00808 (BLAC_BACLI), 1986. Girlich et al., “Value of the Modified Hodge Test for Detection o Emerging Carbapenemases in Enterobacteriaceae”, Journal of Clinical Microbiology, 2012, vol. 50, No. 2, pp. 477-479. Gerrits et al., Helicobacter Ppylori an...