Beta Oxidation of Fatty Acids 1. Purposes and Demands (1) Know about β-oxidation of fatty acids.(2) Master the method to determine β-oxidation as well as its principle. 2. Principle In livers, fatty acids can be transformed into acetyl coenzyme A via β-oxidation. Two molecules of ...
For unsaturated fatty acids, i.e, fatty acids with a single double bond, beta oxidation occurs normally until the enzymes reach the double bond. Enoyl-CoA isomerase then converts the double bond from cis to trans, and beta oxidation continues. Cis and trans describes the orientation of the ...
Fatty acids are activated before oxidation, utilizing ATP in the presence of CoA-SH and acyl-CoA synthetase. Long-chain acyl-CoA enters mitochondria bound to carnitine. Inside mitochondria beta oxidation of fatty acids takes place in which two carbon atoms are removed in the form of acetyl-CoA...
The objective of the present experiments was to test the hypothesis that DCTH is bioactivated by the mitochondrial fatty acid beta-oxidation system to cytotoxic intermediates. Incubation of isolated rat hepatocytes with DCTH produced a time- and concentration-dependent decrease in cell viability. The ...
SY You,S Cosloy §,H Schulz - 《Journal of Biological Chemistry》 被引量: 183发表: 1989年 α-Oxidation of Fatty Acids in Higher Plants A pathogen-inducible oxygenase in tobacco leaves and a homologous enzyme from Arabidopsis were recently characterized (Sanz, A., Moreno, J. I., and Castr...
Degradation of fatty acids having cis-double bonds on even-numbered carbons requires the presence of auxiliary enzymes in addition to the enzymes of the core β-oxidation cycle. Two alternative pathways have been described to degrade these fatty acids. One pathway involves the participation of the ...
Mitochondrial beta-oxidation of fatty acids generates energy by direct electron transfer at the dehydrogenase steps along with the ultimate product of acetyl-coenzyme A that can be further oxidized for ATP synthesis, or conversion to ketone bodies. This review describes the human inborn errors of thi...
Mitochondria catalyze the beta-oxidation of the bulk of short-, medium-, and long-chain fatty a... JK Reddy,T Hashimoto - 《Annual Review of Nutrition》 被引量: 2161发表: 2001年 Rat liver peroxisomes catalyze the B-oxidation of fatty acids Rat liver peroxisomes catalyze the beta oxidation ...
INCREASED BETA-OXIDATION AND OMEGA-OXIDATION OF FATTY-ACIDS IN THE SILVER RUSSELL SYNDROME 来自 国家科技图书文献中心 喜欢 0 阅读量: 10 作者:PJ Willems,I Stolte-Dijkstra,H Schierbeek,R Berger,G Smit 摘要: Pediatric Research publishes original papers, invited reviews, and commentaries on the ...
INCREASED BETA-OXIDATION AND OMEGA-OXIDATION OF FATTY-ACIDS IN THE SILVER RUSSELL SYNDROMEPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model ...