Assessment of miR-30 target pathways revealed a network of genes involved in fatty acid biosynthesis and metabolism. Over-expression of miR-30e in cultured ECs increased fatty acid β-oxidation and the production of reactive oxygen species and lipid peroxidation, while inhibiting the miR-30 family ...
Obesity results in reprogramming of cardiac metabolism that includes impaired glucose uptake and oxidation for a given insulin concentration23. These alterations in cardiac metabolism have been linked to impairments in cardiac relaxation and left ventricular (LV) filling24. Although increased filling pressur...
In vitro experiments have clearly shown that under conditions where ferric iron and unsaturated fatty acids are present, ascorbic acid actually promotes lipid oxidation. Whether this also occurs in vivo is not known. Citrus fruits, green peppers, cauliflower, broccoli, cabbage, and strawberries are ...
Test for glucose and other reducing disaccharides, involving the oxidation of the sugar by an alkaline copper sulphate solution (Benedict’s solution), in the presence of sodium citrate, to give an deep red copper (I) oxide precipitate. Used in urine testing for diabetes. benign tumour A clone...
NADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).NADP is a substance in which nicotinic acid amide adenine dinucleotide...
Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the earliest to be associated w
microbial ecology and functional diversity of natural habitats Keywords: cold adaptation; nitrification; nitrite oxidation; permafrost Introduction Nitrification – the biological oxidation of ammonia to nitrite and further to nitrate is of fundamental importance for the global nitrogen cycle in marine and ...
The present disclosure discloses compounds capable of modulating the activity of α-amino-β-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorder...
Hydroxylation and oxidation of C4 on (−)-limonene produce (−)-carvone (CS 2.10) from Mentha spicata L. (family Lamiaceae Martinov), which at a dose of 200 mg/kg protected rodent against the pain inflicted by acetic acid and formalin via a non-opioid central mechanism probably involving...
During oxidative storage, aldehydes increase significantly, on the one hand due to oxidation of alcohols by a coupled oxidation mechanism involving air oxygen and wine di- and trihydroxyphenols93 and, on the other hand, due to their biosynthesis by veil-forming yeast. This is the case for aceta...