beta-lactam antibiotic (redirected fromBeta-lactam antibiotics) Medical Encyclopedia Related to Beta-lactam antibiotics:beta-lactamase,Aminoglycosides n. Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring. ...
Also provided are pharmaceutical formulations of these thiazolium-substituted compounds and intermediates useful in the preparation thereof.JIYON MAIKERU MOORIN JIYUNIANERUSON JIYOODAN RENAADO
The core part of the structure contains beta-lactam, a four-membered cyclic ring, and it works by interrupting the formation of the bacteria cell wall. The major drawback of this drug is that bacteria develop resistance to this antibiotic by synthesizing a β-lactamase enzyme, which can ...
BRL 17421 is a new semisynthetic beta-lactam antibiotic with an unusual spectrum of antibacterial activity. The compound exhibits exceptional stability to a wide range of bacterial beta-lactamases and is active against the majority of Enterobacteriaceae, including strains highly resistant to many of the...
Meropenem trihydrate(美罗培南三水合物)是一种碳青霉烯类抗生素。在体外对革兰氏阳性和革兰氏阴性细菌的临床分离株有活性,包括肺炎链球菌、流感嗜血杆菌、淋球菌、大肠杆菌、铜绿假单胞菌、艰难梭菌、 和对甲氧西林敏感和耐药的金黄色葡萄球菌(MICs = ≤0.008-8 μg/ml)。
Antibiotic PS-5 is a new beta-lactam antibiotic isolated from fermentation broths of Streptomyces sp. strain A271. The strain was considered to be a new subspecies of Streptomyces cremeus and the name, Streptomyces cremeus subsp. auratil... K Okamura,S Hirata,A Koki,... - 《Journal of ...
such that the active site is inactivated not at all or too slowly to prevent cell-wall synthesis and bacterial growth. Determination of the crystal structure of the low-affinity penicillin-binding protein PBP2a, which mediates beta-lactamantibiotic resistancein staphylococci, has identified the molecul...
aThe beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. beta酮抗药性ceftriaxone从可卡因、安非他明、甲基苯丙胺和clorazepate在花虫类动物禁止物理依赖性和节欲导致的撤退。 [translate] ...
Hospital wastewater is a complex matrix containing a high abundance of bacteria combined with sublethal antibiotic concentrations from clinical settings, which serves as a hot spot for the evolution and dissemination of antimicrobial resistance (AMR), and also a reservoir of novel resistance genes14...
It was initially described as an antiviral antibiotic, but it was later found to inhibit protein secretion at an early stage, probably blocking secretion in a pre-Golgi compartment. Binds to the ARF 1/GDP/Sec7 complex and blocks GEF activity at an early stage of the reaction, prior to ...