Diagnosis and Risk Stratification for Early-Stage HR+/HER2- Breast Cancer Dr Sardesai on Lasofoxifene Plus Abemaciclib in ESR1-Mutant, ER+/HER2– Breast Cancer Dr Ahluwalia on the SURVIVE Trial of SurVaxM Plus Chemoradiation in Newly-Diagnosed Glioblastoma ...
Working in clinical trials also offers a unique opportunity for exposure to what would otherwise be considered rare cases. For instance, we often work with relatively rare tumors over a short time – one of my colleagues once reviewed 1,800 cases of glioblastoma multiforme over a six-...
Survival prospects for patients with glioblastoma remain very poor, which makes it important to understand the effects that surgery has on quality of life and, more specifically, functional independence for patients with high-grade glioma. Indeed, although several early-phase clinical trials of ...
76 DNX-2401 is now undergoing testing in a phase II study combining the virus and pembrolizumab for those glioblastoma patients progressing on initial therapy (CAPTIVE [Combination Adenovirus+Pembrolizumab to Trigger Immune Virus Effects] trial, ClinicalTrials.gov: NCT02798406). ONCOS-102 Another ...
While other studies have been initiated to enhance delivery across the blood–brain barrier (BBB) to treat glioblastoma [24,25,26] using ultrasound parameters higher the diagnostic range. The use of commercially available microbubbles and ultrasound equipment approved for use in diagnostic ultrasound ...
Keywords: magneto hyperthermia; magnetic nanoparticles; glioblastoma; C6 cells; superparamag- netic iron oxide nanoparticles; AMF; intracellular hyperthermia; extracellular hyperthermia; PLL; static magnetic field; dynamic magnetic field 1. Introduction The treatment of cancer remains considered as one of ...