Benjamini和Hochberg于1995年引入了虚警发现率(False Discovery Rate,FDR)的概念,用于在多重假设检验中控制伪阳性发现(FalsePositive)的概率。在科学研究中,多重假设检验经常用于比较多个检验或分析的结果,例如在基因表达分析、药物筛选、神经影像研究等方面。 多重假设检验中的一个关键问题是如何控制伪阳性发现的概率,以...
为了改善这些问题,Benjamini和Hochberg在1995年提出了一种新的方法,即Benjamini和Hochberg错误发现率(FDR)控制法。 第二步:FDR的定义和原理 错误发现率(FDR)是指被错误拒绝的假设中,实际为真实的概率。通俗地说,FDR是关于“错误发现”的概念,即我们实际上拒绝了正确的假设。 Benjamini和Hochberg的方法的核心思想是对...
Executes the Benjamini & Hochberg (1995) procedure for controlling the false discovery rate (FDR) of a family of hypothesis tests. FDR is the expected proportion of rejected hypotheses that are mistakenly rejected (i.e., the null hypothesis is actually true for those tests). FDR is generally ...
The method of Benjamini & Hochberg (1995) and an adaptive version of it are adjusted to this set-up, transforming them to valid |$p$| -value-based, false discovery rate-controlling methods that do not rely on specifying the correlation structure of the explanatory variabl...
您通常不需要重新发明轮子。p.adjust(p, method = 'hochberg', n = length(p))
您通常不需要重新发明轮子。p.adjust(p, method = 'hochberg', n = length(p))
& Hochberg, Y. (1995) Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society, Series B (Methodological). 57(1), 289-300. Cite As David Groppe (2025). Two-stage Benjamini, Krieger, & Yekutieli FDR procedure (...
Yoav Benjamini, Yosef Hochberg First published: 1995 https://doi.org/10.1111/j.2517-6161.1995.tb02031.x Citations: 55,755 PDF Tools Share SUMMARY The common approach to the multiplicity problem calls for controlling the familywise error rate (FWER). This approach, though, has faults, and ...
Benjamini, Y. and Hochberg, Y. (1995)Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. Roy. Statist. Soc. Ser. B 57 289–300 https://www.stat.purdue.edu/~doerge/BIOINFORM.D/FALL06/Benjamini%20and%20Y%20FDR.pdf...
with or outperform the Storey and Tibshirani (2003) linear step-up procedure, as an alternative to the classical Benjamini and Hochberg (1995) procedure... DJ Sorin,MMK Martin,MD Hill,... - 《Biometrical Journal》 被引量: 139发表: 2001年 Adaptive...