(2011) BDNF- trkB signaling in late life cognitive decline and Alzheimer's disease. Transl. Neurosci., 2.Wang H.-Y., Stucky A., Hahn C.-G., Wilson R., Bennett D., Arnold S. BDNF-trkB signaling in late life cognitive decline and Alzheimer’s disease. Transl. Neurosci. 2011; 2 :...
Wang Y, Zhang L, Li S, et al. BDNF-TrkB autocrine loop enhances the viability of senescent cells. Nature Medicine, 2019, 25(8): 1176-1186. Yuan L, Liu J, Zhang Y, et al. BDNF-TrkB signaling pathway in aging and age-related diseases. Neuroscience Letters, 2020, 690: 134-141. Zh...
Wang Y, Zhang L, Li S, et al. BDNF-TrkB autocrine loop enhances the viability of senescent cells. Nature Medicine, 2019, 25(8): 1176-1186. Yuan L, Liu J, Zhang Y, et al. BDNF-TrkB signaling pathway in aging and age-related diseases. Neuroscience Letters, 2020, 690: 134-141. Zh...
关键词:针刺;BDNF/TrkB信号通路;中枢神经系统疾病;缺血性脑卒中;阿尔茨海默病;帕金森病;脊髓损伤;作用机制 Abstract:As a key regulator of neuronal growth, development and synaptic plasticity, BDNF/ TrkB signaling pathway is widely inv...
Alveolar epithelial regeneration is essential for recovery from devastating lung diseases. This process occurs when type II alveolar pneumocytes (AT2 cells) proliferate and transdifferentiate into type I alveolar pneumocytes (AT1 cells). We used genome-w
Zhao J, Wang H, Liu Y, et al. The role of BDNF-TrkB signaling in stem cell aging. Aging Cell, 2019, 18(6): e12938. Chen Y, Zhang Z, Li Y, et al. BDNF-TrkB autocrine loop in muscle cell aging. Cellular and Molecular Life Sciences, 2021, 78(1): 133-142....
TrkB signaling and increased the invasiveness and tumor-initiating capacity of TNBC cells in vitro.Moreover, BDNF cross-activated TrkB and EGFR in cancer cells expressing both receptors, suggesting a novel cooperative interaction between these signaling pathways in TNBC. These studies provide a novel ...
[10]Xia S H, Hu S W, Ge D G, et al. Chronic pain impairs memory formation via disruption of neurogenesis mediated by mesohippocampal brain-derived neurotrophic factor signaling[J]. Biol Psychiatry, 2020, 88(8): 597...
We conclude that activation of BDNF-TrkB signaling pathway is fundamentally important during the CTZ-induction of epileptiform activity both in vitro and in vivo. 展开 关键词: Cyclothiazide BDNF TrkB receptor Epileptiform activity Hippocampal neuron ...
We hypothesized that 1) increasing BDNF/TrkB signaling at the level of the phrenic motoneuron pool by intrathecal \{BDNF\} delivery enhances functional recovery of rhythmic diaphragm activity after SH, and 2) inhibiting BDNF/TrkB signaling by quenching endogenous neurotrophins with the soluble fusion...