and Borga, O.: Plasma protein binding of basic drugs. II. Importance of a, acid glycoprotein for interindividual variation. Clinical Pharmacology and Therapeutics 22: 545–549 (1977).Piafsky, K. M., and 0. Borgl. Plasma protein binding of basic drugs. Clin. Pharmacol. Tber. 22: 545-...
1、 Basic Pharmacology (2%) Basic Pharmacology (4 Questions) Basic knowledge Types of drugs Major cardiovascular responses; Pharmacokinetics Interaction Metabolism 2 The Autonomic Nervous System 自主神经系统自主神经系统 Consists of motor neurons that control multiple internal organs, including the heart Has...
Antibiotics for systemic use constituted a significant proportion of the pharmaceutical waste from several departments, and were the therapeutic group from which most different drugs were identified. Paracetamol accounted for 33.5% of the discarded tablets/capsules in Odense and 12.6% in Svendborg. ...
A family of inhibitors targeting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that catalyses the conversion of HMG-CoA to L-mevalonate. These molecules are mainly used as cholesterol-lowering drugs, but they also have immunoregulatory and anti-inflammatory properties. L-mev...
This study demonstrates the complementary ways in which CTLA4 and PD1 inhibit protein kinase B signalling to reduce glucose uptake and utilization. CAS PubMed PubMed Central Google Scholar Wei, S. C. et al. Distinct cellular mechanisms underlie anti-CTLA-4 and anti-PD-1 checkpoint blockade. ...
Interestingly, rat liver 3α-HSD was found to be a target for nonsteroidal anti-inflammatory drugs (Pawlowski et al, 1991). Cutaneous distribution of steroidogenic isozymes is summarized in Table I. Table I. Cutaneous distribution of steroidogenic isozymes Empty CellIsoenzymes/major cutaneous ...
Home > Section > Chapter Piafsky, K.M. Clinical Pharmacokinetics 5(3): 246-262 1980 ISSN/ISBN:0312-5963 6156048 10.2165/00003088-198005030-00004 042831891 Article emailed within 0-6 h Buy Now for$19.90 Payments are secure & encrypted
2. Analysis by RP-HPLC, using a calibrated solution of FGF2 as a Reference Standard. Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. > ...
A combination of nuclear magnetic resonance (NMR)-based screening and structure-based drug design has yielded the first bona fide BCL-2 homology 3 (BH3) mimetics, including the BCL-2 and BCL-XL dual antagonist navitoclax, which is the first BCL-2 family inhibitor to show efficacy in ...
Although kidney transplantation is a life-saving procedure for patients with kidney failure, it requires the lifelong use of immunosuppressive drugs. These therapies currently used in the clinic to prevent allograft rejection primarily target the adaptive immune system because B and T lymphocytes are ...