Basic Amino Acid Residues in the V3 Loop of Simian Immunodeficiency Virus Envelope Alter Viral Coreceptor Tropism and Infectivity but Do Not Allow Efficient Utilization of CXCR4 as Entry CofactorFIG. 2. Detection of viral proteins in 293T cells transfected with proviral SIVmac239 constructs ...
Basic amino acid residues in the beta-structure region contribute, but not critically, to presynaptic neurotoxicity of ammodytoxin A (2004) Basic amino acid residues in the β-structure region contribute, but not critically, to presynaptic neurotoxicity of ammodytoxin A, Biochim. Biophys. Acta 170...
These results, when taken together, suggest that basic amino acid residues in the common homeodomain of EGAM1 and EGAM1C and the intact structures of the EGAM1 homeoproteins contribute, at least in part, to the nuclear localization of these proteins in mouse ES cells....
These results, when taken together, suggest that basic amino acid residues in the common homeodomain of EGAM1 and EGAM1C and the intact structures of the EGAM1 homeoproteins contribute, at least in part, to the nuclear localization of these proteins in mouse ES cells. 展开 关键词: Crxos1 ...
FIGURE 7. Summary of the functions of the conserved basic amino acid residues and structural changes caused by AdoMet. A, summary of the functions of the conserved basic amino acid residues. The basic amino acid residues categorized under “Discussion” are shown on the TrmH dimer structure. On...
aThe major molecular determinant of pathogenicity is the presence of multiple basic amino acids at the proteolytic cleavage site of HA rendering it cleavable by ubiquitous furin proteases present in many tissues, whereas LPAIVs carry only two non-consecutive basic amino acid residues at the same po...
Roles of conserved basic amino acid residues and activation mechanism of the hyperthermophilic aspartate racemase at high temperature. X-ray crystallography has revealed two similar alpha/beta domains of the aspartate racemase from the hyperthermophilic archaeon, Pyrococcus horikoshii OT3... Yoshida TSeko...
In the previous studies [21, 22], it was proposed that specific basic amino acid residues on the surface of IpTxa are required for the electrostatic interaction of the toxin with RyR1. Particularly, Gurrola et al. [15] suggested the structural domain composed of Lys19-Arg24 followed by Thr...
The active site is located in the cleft between the two domains where two cysteine residues face each other. This arrangement allows the substrate to enter the cleft and enables the two cysteine residues to act synergistically. However, the distance between their thiolates was estimated to be ...
Taking into account the high extend of basic amino acid residues (arginine, lysine, and histidine residues) on the surface of these proteins, we could explain this outcome by a lesser number of arginine residues that could bind ANS in the sample from the H-group, fol...