B-cell lymphoma is a type of blood cancer that affects the B lymphocytes of the immune system. They usually arise in the lymph nodes or in other lymphoid tissue, such as the spleen, bone marrow, blood or other organs. B-cell lymphomas are composed of large B lymphoid cells whose nuclear...
et al. Stromal gene signatures in large-B-cell lymphomas. N Engl J Med 359, 2313–2323, doi: 10.1056/NEJMoa0802885 (2008). 11. Lossos, I. S. et al. Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. N Engl J Med 350, 1828–1837, doi...
Types of B-Cell Lymphomas Causes of B-Cell Lymphoma Who Is at Risk? 3 min read If your doctor tells you that you have B-cell lymphoma, it means you have a cancer that forms in white blood cells called lymphocytes. There's a lot to take in at first, but your doctor can explain ...
Molecular pathogenesis of B-cell lymphomas: an overview M Raffeld - 《Molecular Biology in Cancer Medicine》 被引量: 3发表: 1995年 Molecular Biology of B Cells || Molecular Pathogenesis of B Cell Lymphomas Dalla-Favera,Riccardo 被引量: 0发表: 2015年 Microsatellite instability is rare in B-...
(encoded byAICDA), in cooperation with POLη, induces mutations in actively transcribed genes through the process of aberrant somatic hypermutation (aSHM)14, which affects a substantial number of loci in these cancers relative to other B-cell lymphomas15. As the repertoire of known aSHM targets...
The mandible is an infrequent localisation of primary osseous non-Hodgkin's lymphomas. Few cases of mandibular non-Hodgkin's lymphomas (NHL) have been reported. A rare condition of primary malignant non-Hodgkin's lymphoma of the mandible in 53-year-old man, was reported at the Department of ...
IntroductionPrimary cutaneous B-cell lymphomas (PCBCLs) are made up of a heterogeneous group of B-cell lymphoproliferative diseases confined to the skin at the time of diagnosis with no evidence of extracutaneous involvement. With early diagnosis and adequate treatment, PCBCLs as a group have an ...
Expression profiling has shown 2 main and clinically distinct subtypes of diffuse large B-cell lymphomas (DLBCLs): germinal-center B cell-like (GCB) and ac... R Shaknovich,H Geng,NA Johnson,... - 《Blood》 被引量: 330发表: 2010年 MLN4924, a NEDD8-activating enzyme inhibitor, is activ...
Pharmacy Times: How do T-cell directed therapies work in the context of indolent B-cell lymphomas? Sonali Smith, MD: When we think about T-cell–directed therapies, they really fall into 2 classes that are currently FDA approved. The first is antibody-based therapy, and the other is T-ce...
来源期刊 Journal of Investigative Dermatology 2009 Feb; 研究点推荐 Aberrant Somatic Hypermutation Primary Cutaneous Marginal Zone B-Cell Lymphomas ASHM primary cutaneous marginal zone B-cell lymphoma (PCMZL) diffuse large B-cell lymphoma 引用走势 2010 被引量:17 0...