B-cell lymphoma is a type of blood cancer that affects the B lymphocytes of the immune system. They usually arise in the lymph nodes or in other lymphoid tissue, such as the spleen, bone marrow, blood or other organs. B-cell lymphomas are composed of large B lymphoid cells whose nuclear...
Types of B-Cell Lymphomas There are two types of lymphoma: Hodgkin's lymphoma and non-Hodgkin's lymphoma. Most B-cell lymphomas are non-Hodgkin's lymphoma. B-cell lymphomas come in many types. Some grow quickly and others grow slowly. Your doctor will explain which type you have and how...
B-cell lymphomas are clonal tumors of mature and immature B cells that constitute the majority (80-85%) of non-Hodgkin lymphomas (NHLs). NHLs are a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment. [1] NHL usually originates ...
SummaryCutaneous B-cell lymphomas (CBCL) are the second most common form of primary cutaneous lymphomas. The cutaneous follicle center lymphoma and the cutaneous marginal zone lymphoma (extranodal MALT type lymphoma) account for the vast majority of CBCL and manifest with nodules. These two lymphoma...
Prevalence of IRF4 rearrangement in large B-cell lymphomas of the Waldeyer's ring in adults Diffuse large B-cell lymphoma (DLBCL) is the most common B-cell non-Hodgkin lymphoma (B-NHL) in adults. These lymphomas are classified according to gene ex... S Sebastian,F Leonie,O Franziska,.....
twomaintypesoflymphocytesthatcandevelopintolymphomas: B-lymphocytes(B-cells)andT-lymphocytes(T-cells). DiffuselargeB-celllymphoma(DLBCL)isthemostcommon formofNHL,accountingforupto30percentofnewlydiagnosed casesintheUnitedStates.DLBCLisanaggressive(fast-growing) ...
(encoded byAICDA), in cooperation with POLη, induces mutations in actively transcribed genes through the process of aberrant somatic hypermutation (aSHM)14, which affects a substantial number of loci in these cancers relative to other B-cell lymphomas15. As the repertoire of known aSHM targets...
Molecular pathogenesis of B-cell lymphomas: an overview M Raffeld - 《Molecular Biology in Cancer Medicine》 被引量: 3发表: 1995年 Molecular Biology of B Cells || Molecular Pathogenesis of B Cell Lymphomas Dalla-Favera,Riccardo 被引量: 0发表: 2015年 Microsatellite instability is rare in B-...
Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features. Blood. 1996;87(1):299–307.PubMed 36. Rinaldi A, Mian M, Chigrinova E, et al. Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the ...
Herein, we address the use of interphase FISH and propose an algorithm to aid in diagnosis of aggressive B-cell lymphomas, including the WHO diagnoses of DLBCL, DHL/THL, high-grade B-cell lymphoma, not otherwise specified (HGBL-NOS), and Burkitt lymphoma (BL). We also discuss the current...