B-Cell Lymphoma Symptoms B-cell lymphoma doesn’t always cause symptoms. If you have a slow-growing type, it might take months or years before symptoms start. As abnormal B cells multiply, they can cause areas that have lymph tissue to get bigger. Sometimes you can even feel these lymph ...
Lymphoma, B-CellVascular NeoplasmsBiopsyFatal OutcomeAgedImmunohistochemistryDelayed DiagnosisIntravascular (angiotropic) lymphoma is a unique and rare cutaneous lymphoma in which the malignant T or B lymphoid cells proliferate within the lumens of small blood vessels, primarily in the skin and central ...
Primary mediastinal (thymic) large B-cell lymphoma (PMBCL) is a rare, aggressive subtype of non-Hodgkin lymphoma and has a complex inflammatory microenvironment. Although most patients can be cured with standard-of-care immunochemotherapy, patients who have disease relapse have an unfavorable prognosis...
The morphology of B―PLL in tissues is not well characterized, because initial descriptions of the disease included cases with the t(11;14)(q13;q32) (IGH/CCND1) translocation characteristic of mantle cell lymphoma. 【翻译】骨髓以外组织的B幼...
Non-Hodgkin’s B-Cell LymphomaInguinal LymphadenopathyBackground: In clinical practice and setting of general practice it is common to see patients with leg edema. To correctly identify the etiology of the edema and then properly manage the cause is not always easy. The unilateral lymphedema of ...
Primary B-Cell Lymphoma This is the second most common lymphoidmalignancyin the lung. Patients present with dyspnea,cough, andhemoptysis, but also haveconstitutional symptomsof fever, night sweats, and weight loss. By definition, the tumor does not involve thelymph nodesprimarily. These tumors are...
However, the trial was halted prematurely due to deleterious effects of atacicept in patients with MS who experienced an increase in clinical symptoms in response to atacicept treatment. While unsuccessful, this trial obliges a rethinking of how different B cell subsets participate in MS pathogenesis...
B-cell lymphoblastic lymphoma (B-LBL) is an abnormal proliferation of lymphocyte precursor cells located primarily outside of the bone marrow and peripheral blood, typically in the mediastinum or other lymph nodes. It is often a disease of childhood that presents with lymphadenopathy, fatigue, ...
①效应性B细胞(effector B cell,Beff)可产生自身抗体,如类风湿因子(rheumatoid factor,RF)和抗瓜氨酸蛋白抗体(anti-citrulline protein antibody,ACPA)等,这些抗体形成免疫复合物,沉积在关节中,并通过补体和细胞激活促进炎症过程;②B细胞作为有效的抗原提呈细胞(antigen presenting cell,APC),通过共刺激分子的表达激活...