B-cell lymphoma is a type of blood cancer that affects the white blood cells in the body (B-cells are a type of white blood cell). The two main types of B-cell lymphoma are Hodgkin's lymphoma and non-Hodgkin's lymphoma. B-cell lymphoma can be curable,and it is often treated using...
B-cell lymphomas are hematological malignancies, which develop from B-cells at different maturation stages by the acquisition of genetic changes. These genetic changes are at least in part introduced through somatic mutation machineries which B-cells need to fulfill their physiologic tasks in adaptive ...
ge B‐cell lymphoma Relapse in stage I(E) diffuse large B‐cell lymphomaRelapse in stage I(E) diffuse large B‐cell lymphomaCNSdiffuse large B‐cell lymphomalimited stageMYCrelapsesurvivalDespite a general favourable outcome in limited stage diffuse large B-cell lymphoma (DLBCL), relapses occur...
Zhen Wang3, Li Wang1, Lei Fan1, Dong Hua2,Yao-Yu Chen1, Wei Xu1, Zhi-Hong Zhang3 & Jian-Yong Li1,4 Using an immunohistochemistry (IHC) based method, diffuse large B-cell lymphoma (DLBCL) can be classified into germinal center B-cell (GCB) and non-GCB subtypes...
(Hdac1Δ/+; Hdac2Δ/Δ;Fig. 2). We analysed 8-week old lymphoma-free Eμ-mycmice and first performed flow cytometry analysis of the BM. Interestingly,Hdac1Δ/Δ;Hdac2Δ/+; Eμ-mycmice had significantly reduced blasts at Pro/PreB cell stages (Fig. 5A, upper panels) and displayed a...
B-cell development.Stages of B-cell maturation are indicated by their anatomical site and the ...
In contrast, high-growth fraction lymphomas are characterized by an enhanced proliferative activity, as a result of the deregulation of oncogenes with cell cycle regulatory functions, such asBCL6, in large B-cell lymphoma, or c-myc, in Burkitt lymphoma. Low- and high-growth fraction lymphomas ...
L. Differential effects of bryostatin 1 on human non-Hodgkin's B-lymphoma cell lines. Leuk. Res., 17: 1-8, 1993.Mohammad R. M., Al-Katib A., Pettit G. R. & Sensen- brenner L. L. (1993) Differential effects of bryostatin 1 on human non-Hodgkin's B-lymphoma cell lines. ...
This progress has been the result of better understanding of the molecular basis of normal B-cell development from a progenitor B-cell to memory B-cell or plasma cell and how aberrations at these particular stages lead to a specific subtype of B-cell lymphoma displaying enhanced cell growth ...
CD4+ Th1-cells predominate in low-grade B-cell lymphoma of gastric mucosa-associated lymphoid tissue (MALT type). Scand J Gastroenterol. 2001;36:1198-1203.Riedel S,Kraft M,Kucharxik T,et al.CD4+ Th1-cellS predominate in low-grade B-cell lymphoma of gastric mucosa-associated lymphoid tissue...