参考文献: T.G. Wiggers, G. Westra, T.M. Westers, et al. ZAP70 in B-CLL cells related to the expression in NK cells is a surrogate marker for mutational status. Cytometry Part B, Clinical Cytometry; 86 (2014):280–7. Axler, O., & Porwit,...
In studies concerning the interaction of B-CLL cells and Epstein-Barr virus (EBV), we encountered one patient whose cells had several unusual properties. In addition to the B-cell markers, the CLL cells expressed the exclusive T-cell markers CD3 and CD8 and carried a translocation t(18,22)...
每个B细胞阶段都可能出现淋巴瘤。HSC,造血干细胞;CLL,慢性淋巴细胞白血病;MCL,套细胞淋巴瘤;GCB-DLBCL,生发中心B细胞弥漫性大B细胞淋巴瘤;BL,伯基特淋巴瘤;FL,滤泡性淋巴瘤;PCFCL,原发性皮肤滤泡中心淋巴瘤;PCLBCL,原发性皮肤大B细胞淋巴瘤;NMZL,...
名称:EasySep™ Direct Human B-CLL Cell Isolation Kit 品牌:STEMCELL 规格:For processing 100mL whole blood 产品描述:Immunomagnetic negative selection from whole blood kit 购买数量: 立即购买 产品信息 This kit isolates untouched and highly purified B-CLL cells directly from human whole blood by fully...
We used cells from two B-CLL patients which differed in sensitivity to EBV infection. After 7 days in culture, we studied the CLL cells exposed to the B-cell activators Staphylococcus aureus, IL-2 and/or to EBV for expression of the activation markers CD23, CD39 and the adhesion and ...
慢性淋巴白血病(CLL):这时,如果记忆B细胞发生癌变了,也会发生慢性淋巴白血病(CLL)。但是,由于记忆B细胞的IGHV已经发生了很多突变,因此比起幼稚B细胞癌变,其造成的危害要小。 多发性骨髓瘤(MM):MM是由浆细胞的癌变导致的,一般IGHV的突变频率很高。 文章首发于深圳泛因医学有限公司微信公众号“泛因医学”。
J. C. B-CLL cells express true endogenous E receptor after culture with T-cells and mitogens. Br. J. Haematol., 52: 205- 210,1982.Worman C. P. & Cawley J. C. (1982) B-CLL cells express true endogenous E receptor after culture with T cells and mitogens. Br. J. Haemat. 52...
成熟B细胞肿瘤可分为B细胞慢性淋巴细胞性白血病(B-CLL)、小淋巴细胞淋巴瘤(SLL)、淋巴浆细胞样淋巴瘤(LPL)、套细胞淋巴瘤(MCL)、滤泡淋巴瘤(FL)、结外粘膜相关淋巴组织边缘带B细胞淋巴瘤、弥漫性大B细胞淋巴瘤(DLBCL)、Burkltt淋巴瘤等。 对B细胞肿瘤主要的治疗药物包括抗体药(CD19, CD20, CD22, CD40等),...
IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation[J]. Am J Pathol, 2012, 180(6):2375-2385. IL-10-producing CD1d(hi)CD5(+) B cells, also known as B10 cells, have been shown to possess a regulatory function in the inhibition ...
B-cell chronic lymphocytic leukemia (B-CLL) cells are resistant to apoptosis, and consequently accumulate to the detriment of normal B cells and patient immunity. Because current therapies fail to eradicate these apoptosis-resistant cells, it is essential to identify alternative survival pathways as ...