Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in h...
Expression of Germinal Center B Cell Markers in Bortezomib-Resistant Multiple Myeloma Cellschildrenmisdiagnosistreatmenttype 2N von Willebrand diseaseRegulatory T cells (Treg) that express the transcription factor Foxp3 are enriched within a broad range of murine and human solid tumors. The ontogeny of ...
这里是查看每个亚群的top基因,所以使用FindAllmarkers函数进行分析即可,然后也是使用Scillus进行可视化 ## Top5 genes library(dplyr) markers <- FindAllMarkers(sce, only.pos = TRUE, min.pct = 0.25, logfc.threshold = 0.25) all.markers =markers %>% dplyr::select(gene, everything()) %>% subset(...
Cell surface markers are also used to define the early stages of B-celldevelopment. CD10 (CALLA, the common acute lymphoblastic leukemia antigen) and CD19 areexpressed on immature B cells (pro-B and B precursor) that have begun heavychain rearrangement. ...
Both B cells and CLL cells depend primarily on BCL-2 and are thus sensitive to the BCL2 specific inhibitor venetoclax, while plasma cells and multiple myeloma typically depend on Mcl-1 and would therefore be resistant to venetoclax. However, a subset of myeloma is venetoclax sensitive based on...
Figure 1A: Human B cell development and cellular markers. Prenatal B cell development takes place in the fetal liver; postnatal B cell development originates in the bone marrow (BM). After initial maturation, B cells migrate to the spleen or other secondary lymphoid tissue for fu...
(单细胞的常规分析). We then annotated the cell type for each cluster according to canonical cell markers(依据传统的细胞marker来定义细胞类型) fromCell Markerand assigned these 24 clusters to 15 types of cells, includingendothelial cells, monocytes, macrophages, dendritic cells, B cells, T cells,...
After each purification step (columns) cells were subjected to flow cytometric analysis with indicated surface markers to determine purity. Arrows indicate subsequent gating and numbers percent gated population. (RBC; red blood cell). Extended Data Fig. 2 GCBC show high viability in culture in ...
Marginal zone B cells are strategically positioned at the interface between the circulation and the white pulp of the spleen, where they can mediate a rapid, innate-like humoral response against both pathogens and commensals that breach the mucosal barri
Rheumatic B-cell Markers in Rheumatic Fever/Rheumatic Heart Disease (RF/RHD) Patients: Specificity Associated with Ethnicity. |[dagger]| 119 来自 Semantic Scholar 喜欢 0 阅读量: 16 作者:S Kaur,D Kumar,A Grover,KL Khanduja,NK Ganguly