Although substantial progress has been made in the treatment of B-cell acute lymphoblastic leukemia (B-ALL), the prognosis of patients with either refractory or relapsed B-ALL remains dismal. Novel therapeutic strategies are needed to improve the outcome of these patients. KPT-9274 is a novel ...
【翻译】骨髓涂片显示有90%胞体小到中等的L1原始淋巴细胞,并易见(22%)吞噬红细胞现象。 Flow cytometry study was suggestive of pro‐B-cell acute lymphoblastic leukemia (B-ALL; CD19+TdT+CD10−) with aberrant partial expression of CD13 and CD...
前B淋巴细胞白血病（Precursor B-cell Acute Lymphoblastic Leukemia，B-ALL）是一种起源于骨髓中未成熟前体B淋巴细胞的急性白血病，属于急性淋巴细胞白血病（ALL）的主要亚型（占ALL的80-85%）。 - 细胞来源：B细胞发育早期阶段（前B细胞），停滞在原始或幼稚阶段。 - 特征：骨髓中大量原始/幼稚淋巴细胞增殖，...
急性淋巴细胞白血病(Acute Lymphoblastic Leukemia, ALL)是儿童最常见的恶性肿瘤,尽管目前基于形态学-遗传学-免疫分型-分子分型(MICM)联合化疗后微小残留病(measurable residual diseases, MRD)水平指导的动态危险度分层化疗已经使得90%左右的患...
Precursor B Cell Acute Lymphoblastic Leukemia Acute lymphoblastic leukemia(ALL) is the most common type of childhood cancer, with approximately 6000 new cases diagnosed in the United States each year (Siegel et al., 2014). Most leukemias originate within the B cell rather than the Tcell lineage...
Here we generated 161,986 single-cell transcriptomes to analyse the dynamic changes of B-cell acute lymphoblastic leukaemia (B-ALL) at diagnosis, residual and relapse by combining single-cell RNA sequencing and B-cell-receptor sequencing. In contrast to those at diagnosis, the leukaemic cells at...
英文别名: B-cell Acute Lymphoblastic Leukemia-1 中文名: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA-1人B淋巴细胞急性白血病细胞系保种库(附带STR基因图谱) 中文别名: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA-1人B淋巴细胞急性白血病细胞系保种库(附带STR基因图谱) CBNumber: CB015054216 分子式: 分子量: 0 MOL ...
B-cell Acute Lymphoblastic Leukemia-1Cells;细胞背景资料:详见相关文献介绍;细胞传代方法:1:2传代;细胞生长特性:悬浮生长;细胞形态特性:淋巴母Cells;相关细胞有:SMMC7721Cells、NCI-HUT-460Cells、LSC-1细胞 A.704Cells;细胞背景资料:详见相关文献介绍;细胞传代方法:1:3—1:4传代,每周换液2-3次;细胞生长特性:...
为了攻克这个难题,中国人民解放军西部战区总医院血液科等单位的研究人员在《Heliyon》期刊上发表了一篇名为《Rapid development of acute monocytic leukemia (AML-M5b) with t (9;11)(p22;q23) after chemotherapy for T-cell lymphoblastic lymphoma: A case report》的论文。他们通过研究发现,T-LBL 进展为 AML...
[8]Ting S, Mixue X, Lixia Z, et al. T315I mutation exerts a dismal prognosis on adult BCR-ABL1-positive acute lymphoblastic leukemia, and salvage therapy with ponatinib or CAR-T cell and bridging to allogeneic hematopoietic st...