B-cell Acute lymphoblastic leukemiahematological profilebiochemical profileB-cell acute lymphoblastic leukemia is the most common type of leukemia found in children. Timely diagnosis, white blood cell count, age of onset, and sex are considered the most important prognostic factors in childhood leukemia...
英文摘要 Although most children survive B cell acute lymphoblastic leukemia (B-ALL), they frequently experience longterm, treatment-related health problems, including osteopenia and osteonecrosis. Because some children present with...
ObjectiveTo study the expression levels of ferroportin (Fpn) in lymphoblastic leukemia cells in children with precursor B-cell acute lymphoblastic leukemia (BCP-ALL), and to explore the possible correlations with various clinical features and treatment outcomes. MethodsSixty-four children with newly dia...
【4】 Pui CH. Precision medicine in acute lymphoblastic leukemia. Front Med.2020;14(6):689-700. 【5】Maloney KW, Devidas M, Wang C, et al. Outcome in children with standard-risk Bcell acute lymphoblastic leukemia: results of Children's Oncology...
成熟B细胞非霍奇金淋巴瘤(B-cell non-Hodgkin lymphoma, B-NHL)占儿童和青少年非霍奇金淋巴瘤(non-Hodgkin lymphoma, NHL)的50%~60%。以伯基特淋巴瘤(Burkitt lymphoma, BL)/白血病(Burkitt leukemia, B-AL)和弥漫大B细胞淋巴瘤(diffuse large B-cell lymphoma, DLBCL)最为常见。2011年中华医学会儿科学分会...
前B淋巴细胞白血病（Precursor B-cell Acute Lymphoblastic Leukemia，B-ALL）是一种起源于骨髓中未成熟前体B淋巴细胞的急性白血病，属于急性淋巴细胞白血病（ALL）的主要亚型（占ALL的80-85%）。 - 细胞来源：B细胞发育早期阶段（前B细胞），停滞在原始或幼稚阶段。 - 特征：骨髓中大量原始/幼稚淋巴细胞增殖，...
In the pediatric population, B-acute lymphoblastic leukemia (B-ALL) is the most prevalent childhood hematological malignancy, as well as the leading cause of childhood cancer-related mortality. Advances in cytogenetics utilizing array-based technologies
[8]Ting S, Mixue X, Lixia Z, et al. T315I mutation exerts a dismal prognosis on adult BCR-ABL1-positive acute lymphoblastic leukemia, and salvage therapy with ponatinib or CAR-T cell and bridging to allogeneic hematopoietic stem cell transplantation can improve clinical outcomes....
[8]Ting S, Mixue X, Lixia Z, et al. T315I mutation exerts a dismal prognosis on adult BCR-ABL1-positive acute lymphoblastic leukemia, and salvage therapy with ponatinib or CAR-T cell and bridging to allogeneic hematopoietic stem cell transplantation can improve clinical outcomes....
Precursor B Cell Acute Lymphoblastic Leukemia Acute lymphoblastic leukemia(ALL) is the most common type of childhood cancer, with approximately 6000 new cases diagnosed in the United States each year (Siegel et al., 2014). Most leukemias originate within the B cell rather than the Tcell lineage...