The activation of B cells to secrete antibody by helper T cells (Th) was one of the first cell interactions to be characterized in the immune response. 1 The process has been extensively characterized since its initial description twenty years ago. Two features of this cellular interaction have...
(C) 活性 IgG4-RD 患者的 Tph 细胞中 TIGIT、MAF、TOX 和 CXCL13 水平高于非活性患者或健康对照组。 (D) 血清 IgG4 水平升高的患者中 CD4 T 细胞中 Tph 细胞的百分比较高,Tph 细胞中 TIGIT 的表达较高。 (E) Tph细胞中的TIGIT表达和CD4 T细胞中Tph细胞的百分比与IgG4-RD反应指数(RI)呈正相关。 见...
Do helper T-cells get sensitized? Are helper T-cells activated during B-cell activation? Are lymphocytes activated by helper T-cells? Are helper T-cells phagocytic? Do helper T-cells become cytotoxic T-cells? Do helper T-cells secrete perforin?
B cells are activated by two temporally distinct signals, the first provided by the binding of antigen to the B cell antigen receptor (BCR), and the second provided by helper T cells. Here we found that B cells responded to antigen by rapidly increasing their metabolic activity, including bot...
Signaling Events during Helper T-Cell-Dependent B-Cell Activation .1. Analysis of the Signal-Transduction Pathways Triggered by Activated Helper T-Cell in ... The CD43 lymphocyte surface receptor is involved in the regulation of lymphocyte adhesion and activation. Many CD43 functions remain controvers...
Helper T cells cannot induce ( ) A. B cell proliferation B. B cells differentiate into plasma cells C. The amplification of memory B cell library D. light chain V.J E. B cells produce a class conversion of antibodies 相关知识点: ...
Learn about helper T cells. Discover the helper T cell's function, helper T cell activation, the types of T helper cells, and how these cells are formed. Related to this Question Which cells directly attack other cells? a. T helper cells b. Cytotoxic T cells c. B clone ...
B cells modulate T cells so as to favour T helper type 1 and CD8+ T-cell responses in the acute phase of Trypanosoma cruzi infection. Immunology. ... F Cardillo,E Postol,J Nihei,... - 《Immunology》 被引量: 49发表: 2010年 B cells modulate T cells so as to favour T helper type...
In some B cell leukaemias and lymphomas, malignant B cells utilize BCR signalling for growth and survival. The mechanism of activation of BCR signalling includes continuous BCR stimulation by microbial antigens and/or autoantigens that are present in the tissue microenvironment, oncogenic mutations ...
1.T细胞依赖性活化(T cell-dependent activation) 需要辅助性T细胞(CD4⁺ T细胞)的帮助。 典型过程: 抗原通过BCR被识别并内吞。抗原被处理后呈递在MHC-II分子上。T细胞通过TCR识别MHC-II-抗原复合物,同时提供共刺激信号(如CD40-CD40L结合)。 结果: B细胞增殖、分化为浆细胞和记忆B细胞,并经历胚系中心反应(包括...