cell death, and understanding these interactions is becoming increasingly important in improving cancer therapy and patient outcomes. In this review, we consider how recent discoveries about how autophagy manip
CancerCell deathApoptosisIn every moment of a cell's existence one key question is always asked, "To be or not to be"? Cells constantly weigh up signals from their environment against their own integrity and metabolic status and decide whether to live or die. Such cell death decisions are ...
Escaping programmed cell death is a hallmark of cancer. NF-κB transcription factors are key regulator of cell survival and aberrant NF-κB signaling has been involved in the pathogenesis of most human malignancies. Although NF-κB is best known for its
Escaping programmed cell death is a hallmark of cancer. NF-κB transcription factors are key regulator of cell survival and aberrant NF-κB signaling has been involved in the pathogenesis of most human malignancies. Although NF-κB is best known for its antiapoptotic role, other processes regulating...
Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapies. Adv. Exp. Med. Biol 2014;772:167-88.Reyjal J, Cormier K and Turcotte S: Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapies. Adv Exp Med Biol ...
cancercell differentiationpyroptosisnecroptosisnecrosisCell death was once believed to be the result of one of two distinct processes, apoptosis (also known as programmed cell death) or necrosis (uncontrolled cell death); in recent years however several other forms of cell death have been discovered ...
2023年4月16日,广州医科大学病理生理学教研室、广东省蛋白质修饰与降解重点实验室陈鑫副研究员和刘金保教授团队在Autophagy杂志发表题为"Copper metabolism in cell death and autophagy"的综述文章。作者首先总结了铜离子的关键代谢过程及其在人体生理和疾病中的重要作用,讨论了铜离子如何影响及触发各种类型的细胞死亡(...
主要从事骨与软组织肿瘤诊疗和肿瘤进展调控机制以及转化应用等工作。先后主持国家自然科学基金6项,首都卫生发展科研专项1项,研究成果已在Autophagy、Cell Death Differ、Front Immunol、Front Oncol、J Exp Clin Cancer Res、Cell Death Dis、Cancer GeneTher等期刊上发表。
9. MD Keller,Torres V J ,Cadwell K . Autophagy and microbial pathogenesis[J]. Cell Death and Differentiation, 2020, 27(11):1-15. 10. Warnes G . Measurement of Autophagy by Flow Cytometry[J]. Current Protocols in Cytometry, 2014, 68:9.45.1. ...
The emerging roles of miRNA-mediated autophagy in ovarian cancer Yamin Ding , Xuan Huang & Rongbin Wei Review Article 27 April 2024 | Open Access The crosstalk between mitochondrial quality control and metal-dependent cell death Qi-yuan Zhou , Chao Ren & Yong-ming Yao Article 06 Ap...