Mitophagy-related regulated cell death: molecular mechanisms and disease implications Molin Yang , Xiang Wei & Ding-Sheng Jiang Article 05 July 2024 | Open Access BNIP3-mediated mitophagy boosts the competi
Notably, necroptosis, ferroptosis, and PANoptosis are directly classified as autophagy-mediated cell death. Therefore, regulating autophagy presents a therapeutic approach for treating diseases such as inflammation and tumors that arise from abnormalities in other forms of programmed cell death. This review...
The roles of autophagy in cell death are mainly classified into autophagy- dependent cell death (ADCD) (or autophagic cell death, ACD), which depends on the autophagy mechanism, and autophagy- mediated cell death (AMCD), which depends on other modes of cell death. In ADCD, the unrestricted...
Therefore, to investigate the autophagy-mediated cellular phase transition should be valuable for the comprehensive understanding and further predicting the fate of a cell, i.e., (autophagy-mediated) cell death or survival. Such a view of autophagy as a phase transition is thus expected to ...
2024年5月18日,上海中医药大学贾立军独立通讯在Autophagy在线发表题为“SCFFBXW5-mediated degradation of AQP3 suppresses autophagic cell death through the PDPK1-AKT-MTOR axis in hepatocellular carcinoma cells”的研究论文。该研究首次报...
[8,9,10]. The roles of autophagy in cell death are mainly classified into autophagy-dependent cell death (ADCD) (or autophagic cell death, ACD), which depends on the autophagy mechanism, and autophagy-mediated cell death (AMCD), which depends on other modes of cell death. In ADCD, the...
Cell Rep. Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival Nat Commun. Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy Eur J Pharmacol. Malvidin protects against lipopolysaccharide-induced acute liver injury...
there is increasing evidence that the genetic machinery of autophagy may be essential for cell death in certain settings. We recently identified a novel form of autophagy gene-dependent cell death, termed autosis, which is mediated by the Na+,K+-ATPase pump and has unique morphological features....
Programmed cell death (PCD)鈥攁poptosis, autophagy and programmed necrosis鈥攊s any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing loss (SNHL) that can induce the programmed ...
2022年11月27日,辛辛那提大学医学院肿瘤生物学系管俊林(Jun-lin Guan)团队(羿菲博士(Fei Yi, Postdoctor)为第一作者,现已回国就职于中国医科大学)于Autophagy上在线发表题为Regulation of RB1CC1/FIP200 stability and autophagy function...