in human autaptic iNs. Synapses were identified by Synaptophysin labelling. Only synaptophysin punctae (red) on top of MAP-2 staining (blue) were counted. Scale bars: 5 µm. The numbers of neurons and independent cultures analysed are shown within the bars. Data are expressed as mean ...
We examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal activity, we study how autaptic connections affect activity patterns, and evaluate if cont