IndicationAssociated ConditionsContraindications & Blackbox WarningsPharmacodynamicsMechanism of actionAbsorptionVolume of distributionProtein bindingMetabolismRoute of eliminationHalf-lifeClearanceAdverse EffectsToxicityPathwaysPharmacogenomic Effects/ADRs Interactions Drug InteractionsFood Interactions Products Product Ingredients...
Mechanism Of Action Atropine competitively blocks the effects of acetylcholine, including excess acetylcholine due to organophosphorus poisoning, at muscarinic cholinergic receptors on smooth muscle, cardiac muscle, secretory gland cells, and in peripheral autonomic ganglia and the central nervous system. Phar...
12.1 Mechanism of Action Atropine is an antimuscarinic agent since it antagonizes the muscarine-like actions of acetylcholine and other choline esters. Atropine inhibits the muscarinic actions of acetylcholine on structures innervated by postganglionic cholinergic nerves, and on smooth muscles which respond...
The following adverse reactions have been identified following use of atropine sulfate ophthalmic solution. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposur...
What is diphenoxylate and atropine, and how does it work (mechanism of action)? What brand names are available for diphenoxylate and atropine? Is diphenoxylate and atropine available as a generic drug? Do I need a prescription for diphenoxylate and atropine? What are the side effects of ...
CLINICAL CLOSE-UP ON ATROPINE.Presents information about the anticholinergic drug atropine. Mechanism of action; Indications; Nursing considerations.TeplitzLindaEBSCO_AspNursing
It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Gastrointestinal Anticholinergics/Antispasmodics and Antidiarrhoeals pharmacological group.The Molecular Weight of Atropine (Sulphate) is 694.80. It is weakly acidic drug, 8.85%...
12.1 Mechanism of Action Atropine acts as a competitive antagonist of the parasympathetic (and sympathetic) acetylcholine muscarinic receptors. Topical atropine on the eye induces mydriasis by inhibiting contraction of the circular pupillary sphincter muscle normally stimulated by acetylcholine. This inhibitio...
Atropine was the first effective drug used for symptomatic treatment of Parkinsonism. It has been shown that, unlike gastrointestinal antispasmodics, various synthetic substances such as trihexiphenydil, ethopropazine, benztropine, procyclidine, orphendrine, and biperi-dene, which pass through the blood...
Mechanism of action All anticholinergic agents share the same mechanism of action: they block muscarinic receptors in the striatum. Benztropine (Cogentin) has antimuscarinic, antihistaminic, and local anesthetic effects, competing with acetylcholine and other cholinergic mediators at muscarinic receptors ...