Atropine may also lead to complete urinary retention in patients with prostatic hypertrophy and cause the thickening of bronchial secretions and formation of viscid plugs in patients with chronic lung disease.8 Mechanism of action Atropine binds to and inhibits muscarinic acetylcholine receptors, ...
In the event of accidental ingestion or toxic overdosage with atropine sulfate ophthalmic solution, supportive care may include a short acting barbiturate or diazepam as needed to control marked excitement and convulsions. Large doses for sedation should be avoided because central depressant action may ...
Mechanism Of Action Atropine competitively blocks the effects of acetylcholine, including excess acetylcholine due to organophosphorus poisoning, at muscarinic cholinergic receptors on smooth muscle, cardiac muscle, secretory gland cells, and in peripheral autonomic ganglia and the central nervous system. Phar...
Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the syringe material. 12. Atropine - Clinical Pharmacology 12.1 Mechanism of Action Atropine is an anti...
What is diphenoxylate and atropine, and how does it work (mechanism of action)? Lomotil is a combination of two drugs, diphenoxylate and atropine. It is used to treat acute diarrhea (diarrhea of limited duration). Diphenoxylate is a man-made narcotic chemically related to meperidine (Demerol)...
Atropine is primarily used for its anticholinergic effects, which include blocking the action of acetylcholine in the body. This mechanism of action helps to counteract the effects of certain nerve agents and pesticides. Atropine is commonly used in the field of medicine, particularly in emergency ...
Atropine is the derivative of Atropine (Sulphate)Atropine is the derivative of Atropine (Sulphate) It is of Semi Synthetic origin and belongs to Tropane Alkaloid. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Gastrointes...
by po. The Neostigmine-induced hyperperistalsis of the small intestine was inhibited and the inhibitory effect of Atropine enhanced by ip and sc administration of YT suggesting the mechanism of YT involved the antagonism of Ach. But the contraction of isolated rabbit ileum was not inhibited by YT...
Mechanism of action All anticholinergic agents share the same mechanism of action: they block muscarinic receptors in the striatum. Benztropine (Cogentin) has antimuscarinic, antihistaminic, and local anesthetic effects, competing with acetylcholine and other cholinergic mediators at muscarinic receptors ...
12.1 Mechanism of Action Atropine acts as a competitive antagonist of the parasympathetic (and sympathetic) acetylcholine muscarinic receptors. Topical atropine on the eye induces mydriasis by inhibiting contraction of the circular pupillary sphincter muscle normally stimulated by acetylcholine. This inhibitio...