followed by ATP synthesis and ATP release. This concept recognizes that theβ-subunit can exist in three conformations: open, tight, or loose forms. These forms correspond to the binding, synthesis, and release of ATP and are driven by the rotation of theγ-subunit. The hydrolysis of ATP wi...
Besides a sequential ATP hydrolysis cycle, two other models are put forward to explain how AAA+ ATPases couple ATP hydrolysis to mechanical force to exert their function: the AAA+ lTag is suggested to act via concerted (all-or-none) nucleotide binding and hydrolysis that occurs simultaneously i...
Shen)], (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) ATP Hydrolysis-Dependent Multidrug Efflux Transporter: ... P Idoi - 《Current Drug Metabolism》 被引量: 0发表: 0年 Phylogeny of multidrug transporters We currently recognize five large ubiquitous superfamilies and...
The ATP hydrolysis by HpyAII.M1 was measured by thin layer chromatography on polyethylenimine cellulose plates. Briefly, a reaction mixture (10 μL) contained 50 mM Tris-HCl (pH 7.5), 2 mM MgCl2, 2 mM DTT, 50 μg/mL BSA, 50 μM cold ATP, 0.008 μCi γ-P32ATP with increasing amou...
Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Mammalian Nucleoside Transporters. Wei Kong,Karen Engel,Joanne Wang. Current Drug Metabolism . 2004Kimura Y: (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) ATP Hydrolysis-Dependent Multidrug ...
Two conformations captured under ATP hydrolysis conditions in the absence of substrate The sequential and the concerted mechanisms differ substantially, as the former calls for different nucleotides simultaneously bound within the heptameric mBcs1L and the latter mandates uniform nucleotide states. Therefore,...
ATP Synthase | Definition, Function & Location from Chapter 9 / Lesson 11 54K What is ATP synthase? Learn the ATP synthase definition and see its characteristics and various properties. See common ATP synthase types and examples. Related to this QuestionWhat...
biochemistry - the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton ...
ATP Lesson for Kids: Definition & Biology from Chapter 2 / Lesson 23 42K Learn about ATP, the adenosine triphosphate molecule the cells use as energy. Discover how mitochondria make ATP by using oxygen to break down glucose molecules into ATP during cellular respiration. Related...
(copper-transporting ATPase 2; Wilson ATPase) and belongs to the same family of P-type ATPases. These pumps actively transport copper cations acrosslipid bilayers, using the energy obtained from ATPhydrolysis[1]. They both play a role in maintaininghomeostasisof copper, a metal critical to ...