AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear resp... Nuclear respiratory factor 1 (NRF-1) is one of the key transcription factors implicated in mitochondrial biogenesis by activating the transcription of...
This invention relates to screening assay methods that can be applied to broad members of the protein kinase gene family and are useful in the detection and evaluation of kinase inhibitors.YINGLING, JEFFREY DAVID\nBOEHRINGER INGELHEIM PHARM. INC....
Phosphorylated peptides are easily recognized within the MS spectrum owing to the presence of doublets separated by 6.01 Da; representing versions of the peptide modified by ATP and gamma((18)O4)-ATP. Standard peptides phosphorylated using gamma((18)O4)-ATP via in vitro kinase reactions showed ...
an enzyme that catalyses a process of synthesis Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 Want to thank TFD for its existence?Tell a friend about us, add a link to this...
Transfer of the gamma-phosphoryl group of ATP to riboflavin is catalyzed by flavokinase, which prefers Zn(II), and is essential in the biosynthesis of the flavocoenzyme, FMN. To study the mechanism and steric disposition of ATP binding, adenosine 5'-O-(2-thiotriphosphate) (ATP beta S) and...
Rhesus antibody Rh PI3 Kinase p110 beta 0脂酰肌醇激酶(PI3Kβ)抗体 规格 0.1ml Mouse Anti-human IgG/ Biotin生物素化小鼠抗人IgGMulti-class antibodies规格: 0.1ml 关键字:ATP结合蛋白家族6抗体;Anti-ABCB6;0.1ml/100μg 0.2ml/2;1mg/1ml; ...
The kinetic mechanism of turkey gizzard smooth muscle myosin-light-chain kinase was investigated using the isolated 20-kDa light chain of myosin as substra... A Sobieszek - 《European Journal of Biochemistry》 被引量: 69发表: 1991年 Regulation of smooth-muscle myosin-light-chain kinase. The ki...
The in-gel analysis displayed kinase domains of two receptor-like kinases (RLKs) at a lower than expected molecular weight, indicating that these RLKs lost the extracellular domain, possibly as a result of receptor shedding. Analysis of modified peptides using a gel-free platform identified 242 ...
AS-604850是一种选择性的,ATP竞争性的PI3Kγ抑制剂,IC50为250 nM,作用于PI3Kγ比作用于PI3Kδ/β选择性高80倍以上,作用于PI3Kγ比作用于PI3Kα选择性高18倍。An ATP-competitive inhibitor of PI 3-kinase γ. AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-...
Unidirectional fluxes from ATP to phosphocreatine, catalyzed by the MM isoenzyme of creatine kinase, were measured by both the 31P-NMR saturation transfer technique and radioisotope tracer ([gamma-32P]ATP) method. It was found that at 30... VV Kupriyanov,NV Lyulina,S Aya,... - 《Febs Le...