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impact on pollen fertility as well as plant growth and development, indicating its exclusive role as a toxin (Supplementary Fig.11). Further, F1plants from the cross of DJY1orf3with NIL-qHMS1were still semi-sterile whereas those F1plants from the cross of DJY1 with NIL-qHMS1orf3were ful...
有研究尝试以 Poneratoxin 为基础,开发新型的镇痛药 。虽然 Poneratoxin 本身具有极强的毒性,直接用于人体治疗不可行,但通过对其结构进行改造,设计合成具有类似作用机制但毒性较低的小分子或多肽类似物,有望成为新型镇痛药的研发方向 。此外,在农业领域,鉴于 Poneratoxin 对昆虫神经系统的作用,科学家正在探索将...
多肽合成:Poneratoxin(cas:137084-94-7)Poneratoxin 是电压门控钠通道 (NaV,NaV1.6 和 NaV1.6 的 EC50 为 97 nM 和 2.3 µM) 的调节剂,可降低激活的电压阈值并抑制通道失活,增强神经元的兴奋性,并导致疼痛信号的传递。英文名称:Poneratoxin CAS号:137084-94-7 分子式:C129H215N33O31S...
黄曲霉毒素M1 ES灵敏检测试剂盒Aflatoxin M1 Extra Sensitive ELISA 检测牛奶、绵羊奶、山羊奶及其制品中的黄曲霉毒素M1 黄曲霉毒素M1 BF 婴幼儿食品检测试剂盒Aflatoxin M1 Baby Food ELISA 检测牛奶、绵羊奶、山羊奶及其制品中的黄曲霉毒素M1,符合欧盟和亚洲对婴幼儿食品法规限量的规定。
Gateway cloning employs the use of the ccdb toxin and has low colony numbers, making it difficult to apply at scale to clone libraries of cDNA vectors. In this protocol, we describe MegaGate, a toxin-less Gateway technology capable of robust cDNA library cloning that is efficient, cheap, an...
Here, we show that Yersinia pseudotuberculosis secretes an effector, CccR, that can act both as a toxin and as a transcriptional factor. The effector is secreted by a type VI secretion system (T6SS) and can enter nearby cells of the same species and other species (such as Escherichia coli...
poneratoxin CAS号: 137084-94-7 英文名: poneratoxin 英文别名: poneratoxin;L-Argininamide, L-phenylalanyl-L-leucyl-L-prolyl-L-leucyl-L-leucyl-L-isoleucyl-L-leucylglycyl-L-seryl-L-leucyl-L-leucyl-L-methionyl-L-threonyl-L-prolyl-L-prolyl-L-valyl-L-isoleucyl-L-glutaminyl-L-alanyl-...
In this study, we investigated the action of a toxin purified from; PhTx2 fraction, called PnTx2-6 or δ-CNTX-Pn2a, on L-Glu release from rat; brain cortex synaptosomes, as well as its ability to induce blood-brain barrier permeability. PnTx2-6 increased L-Glu release from rat ...
If one of the partners produces a toxin or virulence factor, it is a prerequisite that not only the producing organism, but also the symbiotic partner is resistant or insensitive to the chemicals released. Thus, another important issue is raised: Correspondence: C Hertweck, Department of ...