Gene Typeprotein-coding gene Uniprot IDQ9H1Y0 Pathway/Libraryothers Gene SummaryThe protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes,...
Gene ID: 9474 种属 Homo sapiens 基因序列编号: NM_004849.4 基因描述 Homo sapiens autophagy related 5 (ATG5), transcript variant 1, mRNA DNA编码区: atgacagatgacaaagatgtgcttcgagatgtgtggtttggacgaattccaacttgtttc acgctatatcaggatgagataactgaaagggaagcagaaccatactatttgcttttgcca agagtaagttatttgacgttggtaact...
Gene SummaryThe protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control af...
ATG5(Autophagy related gene 5)基因是一种自噬相关基因,是形成自噬体的重要基因,ATG5基因的表达对自噬调控的成熟有重要作用.本研究中通过克隆,首次得到太平洋鳕Gadus macrocephalus ATG5 cDNA部分序列,该序列长为895 bp,含有完整的开放阅读框(Open reading frame,ORF),编码275个氨基酸,其编码的蛋白质相对分子量约为32...
英 文名ATG5 gene knockout Raji cell pool (non monoclonal) 规格1T 品 牌圣尔生物share-bio 一键复制产品信息 产品编号名称包装品牌目录价促销价货期数量购物车 SB-KO17111ATG5基因敲除Raji细胞pool(非单克隆) 基因水平验证KO效率>70%(如需WB验证加3000元及时间)ATG5 gene knockout Raji cell pool (non monocl...
关键词:慢病毒;基因;基因敲低;自噬;蛋白;细胞学;细胞群;巨噬细胞 Construction of a stable Atg5 gene knockdown cell line in RAW 264.7 cells by lentivirus infection Xian Guoyan, Chen Weishen, Zhang Ziji, Ye Yongyu, Pan Baiqi, Zheng Linli, Sheng Puyi Department of Joint Surgery, First Affiliated...
What We Have Learned About Pancreatic Cancer From Mouse Models Figure 4 Oncogenic KRAS and inflammation Volume 142, Issue 4, Pages e9 (April 2012) Moorthy P. Ponnusamy, Surinder K. Batra Gastroenterology Unusual Case of an Upset Stomach
例如在肝细胞中，上调Ａｔｇ５的表达量可促进细胞自噬，从而减少内质网应激（ＥＲ）介导的损伤，这是治疗脂肪性肝炎的一个新策略。本文就Ａｔｇ５通过调控自噬参与常见肝脏疾病的内在机制做一总结。关键词 自噬；Ａｔｇ５；肝脏疾病；作用机制 中图分类号 Ｒ７３５ 肝脏是人体最大的实体器官，多种损伤因素如病毒...
然而,对大豆自噬途径的研究鲜有报道。本研究利用大豆豆荚斑驳病毒(bean pod mottle virus,BPMV)介导的基因沉默技术,对大豆自噬相关基因5 (autophagy-related gene 5,ATG5)同源基因进行沉默。结果发现,经暗处理的GmATG5沉默植株叶片上积累过量的ATG8蛋...
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage[J]. J Biol Chem, 2011,286(52):44380-44390. DOI: 10.1074/jbc.M111.257519 . 返回引文位置Google Scholar 百度学术 万方数据 [25] ...