FOX1 (Fox-1 Homolog A, Ataxin-2-binding Protein 1, A2BP1, A2BP, Hexaribonucleotide-binding Protein 1, HRNBP1, RNA Binding Protein Fox-1 Homolog 1, RBFOX1) 供应商 MyBioSource 产品货号 MBS643651 产品报价 ￥询价/0.1mL ￥询价/5x0.1mL ￥询价/其它规格 ...
In Drosophila, a conserved atx2 gene is essential for animal survival as well as for normal RNP-granule assembly, translational control, and long-term habituation. Like its human homolog, Drosophila Ataxin-2 (Atx2) contains polyQ repeats and additional intrinsically disordered regions (IDRs). We ...
Mlle domains are found in all eukaryotic cytoplasmic poly(A)-binding proteins and uniquely in two other proteins as follows: a ubiquitin ligase UBR5 (also known as HYD, EDD, or Rat100) and a distant PABP homolog RRM4 in filamentous fungi (4, 5). Most proteins that contain PAM2 motifs...
HomologInvolvementUbiquitinThe present invention provides a novel method for treating neurodegenerative disease in mammals. This method involves the introduction of a therapeutic effective amount of a chaperone, a chaperone-like-compound or a compound which increases proteasome activity into the neurological ...