Computational chemical biology and drug design: facilitating protein structure, function, and modulation studies. Med. Res. Rev. 38, 914–950 (2018). Article ADS PubMed Google Scholar Zheng, M. et al. Computational methods for drug design and discovery: focus on China. Trends Pharmacol. Sci...
With the accumulation of large-scale molecular and cell biology datasets, coming from ever-growing literature, omics experiments and high-throughput screenings, new frameworks for integrative data analysis are necessary. For a given biological entity (e.g., a gene), we are now able to stack mul...
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Acknowledgements The studies were supported by grants from Academy of Finland (318327) and Sigrid Juselius Foundation for TTM. The...
As a counterpoint, the authors do note that even though many molecular biology highly cited articles were done in 1976, there has been extremely much innovation since then however it may take a lot more in experiments and money to gain the level of citations that those papers produced, and ...
Figure 1. Structure and characterisation of EVs. (A) Scheme of formation, release, structure, and cargo of EVs. (B) Concentration and size of particles by nanoparticle tracking analysis in a sample of EVs. (C) Immunofluorescence of an EV sample with CD81 as a specific EV marker (green) ...
The simplest scheme that qualitatively describes the catalytic mechanism of MnSOD is as follows (eqs1-4). The oxidation of superoxide to oxygen is a single process at the same rate constant k1 in both fast and slow cycles. In its reduced form, MnSOD reacts with O2•− through two ...
Jessica B. Spinelli1,2, Haejin Yoon1, Alison E. Ringel1, Sarah Jeanfavre2, Clary B. Clish2, Marcia C. Haigis1* 1.1Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. 2.2Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. ...
(YCH11) First examination June First teaching September 2018 First examination from January 2019 First certifi cation from August 2019 (International Advanced Subsidiary) and August 2020 (International Advanced Level) Edexcel, BTEC and LCCI qualifications Edexcel, BTEC and LCCI qualifications are ...
In this paper, the diseases of bone tissue are described, in the treatment of which calcium phosphate cements can be used as carriers of functional substances. Knowledge of the pathogenesis of diseases and the methods of treatment used—in particular, drug therapy—can help develop the concepts ...
answers. The pattern of questions set is similar for every year and you should familiarise yourself with the pattern. Usually, the same type of questions will have similar mark scheme, so this can help you when answering exam questions. You should remember the answers for questions that are ...