Delivery of very small amounts of reagents to the near-field of cells with micrometer spatial precision and millisecond time resolution is currently out of reach. Here we present μkiss as a micropipette-based scheme for brushing a layer of small molecul
We have added additional metrics in each release to further improve the usefulness of the dataset. When data from an individual have been published in multiple studies using the same methodology such as in-solution enrichment, the AADR typically includes only the best quality version which is ...
1c), which was further confirmed by analyzing ULK1 mRNA expression in a large cohort of PDA patients using the TCGA database (Additional file 1: Figure S1a). Meanwhile, we found that PVT1 was dramatically up-regulated in 20 PDA tissues compared with the corresponding non-tumor tissues (Fig...
Using Vip3Aa35 as a reference, four additional Vip3 target proteins, namely Vip3Af1, Vip3Ag, Vip3Ca2 and Vip3Ba1, were selected whose amino acid sequences showed between 90 and 60% identity to vip3Aa35. The screening of the Australian Bt collection for genes encoding the target Vip3 ...
To achieve our goal of a current estimate of annual worldwide UAPP, we carried out a systematic review of the scientific literature and additionally used publicly available mortality data from the WHO. This systematic review is based on a protocol (supplementS1) according to the Preferred Reportin...
Additional information Competing interests There was no conflict of interest in the manuscript. Authors’ contributions HQT and ZMH conceived and designed the experiment. XJH and SY carried out the majority of experiments in vitro. YYM collected data and drafted the manuscript with the support of ...
supportive relationships that enable students to take advantage of productive learning opportunities in cognitive, social, and emotional domains, plus additional supports (physical, social, emotional, and/or academic) needed to address individual circumstances that need attention at a moment in time to ...
The goal of this additional cleaning step was to further reduce the presence of powdery corrosion products and tenaciously adhered coating residue that may negatively affect proper adhesion of the new coating. Additional conservation treatment As some of the Morse statue’s surfaces were not easily ...
In addressing this question, the Article re- examines Additional Protocol I's Article 44(3) and adopts an interpretation thereof that better comports with its object and purpose than those previously prevalent. After exposing the limitations of relying solely on drafting history to understa...
Foundational principle 1: NCS are nature-based Foundational principle 2: NCS are sustainable Foundational principle 3: NCS are climate-additional Foundational principle 4: NCS are measurable Foundational principle 5: NCS are equitable Monitoring and policy considerations NCS exemplar Outstanding challenges Co...