B1 cellsanti-Sm antibodyWe report a patient with reticular dysgenesis (RD) who received an HLA-identical marrow graft and remained free of infection in spite of incomplete haematological recovery. Mixed chimerism was achieved and resulted from the presence of autologous B cells and monocytes and ...
In conclusion, deficiencies of B cells, NK cells, monocytes, MDCs, PDCs, basophils, eosinophils, and/or IgA plasma cells appear to predispose to postengraftment infections. 展开 关键词: Immune cells Monocytes Infections Hematopoietic Transplantation ...
In addition, circulating neutrophils were drastically reduced in these DKO mice on Western diet, while expansion of inflammatory monocytes and splenic Th1 or Th17 lymphocytes was not affected. These data reveal, for the first time, a pathogenic role of γδT cells in early atherogenesis in ApoE ...
In the livers of mice given neutrophils, eosinophils, B cells, or T cells, all of the EGFP cells were CD45. The majority of EGFP cells in the nonparenchymal cell fraction purified from the livers of mice given Ly6Cc-kit monocytes contained lipid droplets and were positive for glial ...
The results indicated that B cells, T cells (including BoT4+ and BoT8+ cells), and null cells but not monocytes or neutrophils were transformed in vitro after infection with T. parva. After transformation, peripheral blood T cells and T-cell clones retained expression of most or all of ...
PURTON LE: 'Monocytes are the likely candidate " stromal " cell in G-CSF-mobilized peripheral blood' BONE MARROW TRANSPLANT. vol. 21, 1998, pages 1075 - 1076LE Purton,M Mielcarek,B Torok-Storb.Monocytes are the likely candidate ‘stromal’ cell in G-CSF-mobilized peripheral blood. Bone ...
(CLRs and Siglecs) on each MNP subset obtained via enzymatic digestion (for immature cells) or spontaneous migration (for mature cells). We also included MDDC and MDM derived in vitro from blood CD14 monocytes which are commonly used as model cells (Fig.3C). Importantly, we used appropriate...
Uniquely, this study has also determined the association of B.pseudomallei to host cells invivo using flow cytometric techniques. Neutrophils were found to be the predominant cell-type exhibiting B.pseudomallei antigens during infection and it is likely that bacteria have been internalised. This ...
cells undergoing OIS (Fig.2a,b).COPB2depletion also killed IMR90 cells undergoing doxorubicin-induced senescence (Fig.2c). COPI-coated vesicles consist of multiple subunits25, and depletion of the COPI subunitCOPG1(Supplementary Fig.2b) also killed IMR90 cells undergoing OIS and doxorubicin-...
(p.i.; Fig.1a). Similarly, PR8 infection could also induce beaded apoptopodia and ApoBD formation by primary human CD14+monocytes (Fig.1b, c). To validate that apoptotic cells were indeed infected, we confirmed the presence of the IAV proteins nucleoprotein (NP) and haemagglutinin (HA) ...