We used three-dimensional organotypic culture to compare differentiation of HPV16-immortalized epithelial cell lines derived from ectocervix, TZ, and endocervix. We show that immortal cells from TZ or endocervix form epithelia that are more dysplastic than immortal cells from ectocervix. A higher ...
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Human cell lines are produced by immortalising a human undifferentiated or precursor cell of a given tissue type using an immortalising agent which includes or has an associated control element whereby activation of the control element terminates immortalisation and allows differentiation of the ...
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To overcome this technical barrier, immortal human cell lines are often derived from tumors or produced by transformation with viral oncogenes such as SV40... MM Ouellette,McDaniel Lisa D.,WE Wright,... - 《Human Molecular Genetics》 被引量: 454发表: 0年 Molecular characterization of inter-...
immortal cells still have a death program established by reprogramming the normal cells’ death program, studies using these cells with an already-changed death program can only provide us with already-altered mechanisms. More complicatedly, different cell lines, no matter whether they are derived fr...
We studied the cytotoxic effect of various anticancer agents on lymphoblastoid cell lines transformed by Epstein-Barr virus. Post-immortal N0005 (post-N000... Robbins,R April 被引量: 0发表: 1987年 Population Pharmacological Profiles Of AML Treatments In Patient Samples By Automated Flow Cytometry;...
Out of 210 cancers analyzed, 169 were primary tumors, 2 were early cultures, and 39 were immortal cancer cell lines. Pre 多数体壁变化预计是“对oncogenesis不贡献的乘客”,但是证据为“贡献对癌症的发展的司机”变化在119个基因被发现了。 出于被分析的210癌症, 169是主要肿瘤, 2是早期的文化,并且39是...
cell lines by immortalizing them by introducing SV-40 T antigen or harvesting cells from ImmortoMouse7. However, no study on the primary culture of adult murine PDL cells without induction of transformation has been reported. It has been shown that stem/progenitor cells can be cultured without...
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