Ponders whether somatic stem cells are pluripotent or lineage-restricted. Capability of fetal and adult neural stem cells (NSCs) in differentiating into hematopoietic cells; Ability of stem cells to exhibit multi-lineage differentiation; Demonstration that hematopoietic competence is not a consistent ...
摘要: A defined cultivation system was developed for the differentiation of pluripotent embryonic stem cells of the mouse into spontaneously beating cardiomyocytes, allowing investigations of chronotropic responses, as well as electrophysiological studies of different cardioactive drugs in vitro....
Purpose: The primary objective of this study was to reproduce and validate the harvest, processing and storage of peripheral blood stem cells for a subsequent cartilage repair trial, evaluating safety, reliability, and potential to produce viable, sterile stem cells. Methods: Ten healthy subjects (...
aAutism spectrum disorders (ASD) are complex neurodevelopmental diseases in which different combinations of genetic mutations may contribute to the phenotype. Using Rett syndrome (RTT) as an ASD genetic model, we developed a culture system using induced pluripotent stem cells(iPSCs) from RTT patients...
There are two main types of stem cells found in bone marrow, which include: Hematopoietic stem cells: function to produce various types of blood...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
The recent derivation of in vitro derived sperm and oocytes from pluripotent stem cells in the mouse model represents a major breakthrough in the field and substantiates the critical relevance of stem cells as a potential alternative resource for treating infertility. Although the past years have ...
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.doi:10.1371/journal.pone.0125544Human induced pluripotent stem cells (hiPSCs) could be used to generate autologous cells for ...
X.M. Wang, et al., The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent... XM Wang,WY Yik,P Zhang,... - 《Stem Cell Research & Therapy》 被引量: 28发表: 2012年 Induced Pluripotent Stem Cell Models from ...
Mesenchymal stromal/stem cells (MSCs) regulate the function of immune cells; however, their role in regulating virus production from latently-infected MACs & THLs is not known. We documented that exposure to MSCs or their conditioned media (MSC-CM) rapidly increased HIV-1 p24 production from ...
Scientists at McMaster University have discovered that human stem cells made from adult donor cells "remember" where they came from and that's what they prefer to become again. This means the type of cell obtained from an individual patient to make pluripotent stem cells, determines what can be...