Boyce Rensberger
Cancer cells:Cancer cells are cells that have acquired mutations in their DNA machinery that allow the cells to divide unregulated. Almost any cell type has the potential to become cancerous.Answer and Explanation: There has been much debate over the definition of aliveness in organisms. A few...
- 《Cancer Research》 被引量: 125发表: 1997年 Th induction of thioguanine-resistant mutants of Chinese hamster cells by gamma-rays The induction of mutation to purine analogue resistance was assessed in Chinese hamster V79-4 cells exposed to γ-radiation. After irradiation, the cells were grown...
“driver”mutations contributing to the development of the cancers in 119 genes. Out of 210 cancers analyzed, 169 were primary tumors, 2 were early cultures, and 39 were immortal cancer cell lines. Pre 多数体壁变化预计是“对oncogenesis不贡献的乘客”,但是证据为“贡献对癌症的发展的司机”变化在...
We demonstrate that ART occurs relatively early during cancer evolution and that ART may have a stronger correlation with mutation acquisition than alterations in chromatin structure.Similar content being viewed by others Mutational signatures association with replication timing in normal cells reveals ...
cancer stem cells.22–25 Although several laboratories have explored the suppressor roles of miR-34 family in cancer stem cells of various solid tumors such as colon, breast, pancreas, prostate, glioma and non-small cell lung cancer,24,26–29 the role of miR-34 family in ovarian cancer ...
Selective inactivation of a FADD-dependent apoptosis and autophagy pathway in immortal epithelial cells Although evasion of apoptosis is thought to be required for the development of cancer, it is unclear which cell death pathways are evaded. We previously id... J Thorburn,F Moore,A Rao,... 被...
For cancer treatment, monoclonal antibodies have tremendous potential, because they can be blended with radioactive agents or other compounds and introduced in the body, targeting thecancer cellsand the cancer cells alone. Products used in medical treatment all have names which end in -mab, for “...
Stig Bojesen, Georgia Chenevix-Trench, Alison Dunning and colleagues report common variants at the TERT-CLPTM1L locus associated with mean telomere length measured in whole blood. They also identify associations at this locus to breast or ovarian cancer
strong early- or mid-game Legendary minions that hit the board and do their duty, bravely falling in battle to fight for control of the board. When their Deathrattle is triggered, a vastly-upgraded version of themselves is shuffled into your deck. All nine original classes have a u...