This family of genes encodes the AP transcription factors where the binding motif is well conserved but other sequences may vary. These proteins bind to 5′-TGANTCA-3′ consensus in DNA. AP2 binds only to TC-II but not to TC-I of the two identical and adjacent TC motifs (5′-TCC...
Retroviruses integrate into a shared, non-palindromic DNA motif Article 14 November 2016 Repression of Human T-lymphotropic virus type 1 Long Terminal Repeat sense transcription by Sp1 recruitment to novel Sp1 binding sites Article Open access 03 March 2017 References Bellas R, Hopkins N, Li...
其中, (A)SP1的Motif图; (B)通过JASPAR预测lncRNA AFAP1‑AS1启动子序列中的SP1结合位点; (C)ChIP测定证实SP1与P3处的lncRNA AFAP1‑AS1启动子区结合; (D)通过蛋白质印迹证实了ov‑SP1载体对SP1的过度表达; (E)通过双荧光素酶测定法测定结合位点P3。
For eukaryotic systems, however, some DNA motif(s) are capable of binding to a family of related factors, thus making it difficult to identify the factor actually binding on the chromatic DNA in vivo and modulating the local transcription processes. To resolve this matter, we have refined a ...
Slit2 enhances the interaction of the SH3 domain in srGAP1 with the CC3 motif in Robo1, and this localization may induce inactivation of a small GTPase protein Cdc42, a member of the Rho-GTPase family, by converting the active GTP-bound form of Cdc42 to the inactive GDP-bound form of...
| actc | actgene | active motif | activemotif | Adam Equipment, Inc. | addgene | ademtech | adg | adi | adipogen | adooq | advanced bioscience laboratories, inc | advanced biotechnologies | advanced biotechnologies incorporated | Advanced Ceramics Manufacturing | advanced chemtech | Advanced Env...
| actc | actgene | active motif | activemotif | Adam Equipment, Inc. | addgene | ademtech | adg | adi | adipogen | adooq | advanced bioscience laboratories, inc | advanced biotechnologies | advanced biotechnologies incorporated | Advanced Ceramics Manufacturing | advanced chemtech | Advanced Env...
zipper(bZIP、motif.As a trans・ factor AP-l Canregulate the transcriptionalefficiency ofthe targetedgenebybinding withtheconsensus sequence “TGAGTCA”directly or indirectly.Itplays an important roleinthe regulation of genetranscription.AP-lactivity ...
JunD, when forming homo or hetero dimers with the Jun family of proteins, prefers binding to the 7-mer phorbol 12-O-tetradecanoate-13-acetate (TPA)-responsive element (TRE) motif TGA[C/G]TCA; while it binds to 8-mer cAMP-responsive element (CRE) motifs TGACGTCA when it forms hetero ...
We demonstrate that there are two closely located AP1 binding sites residing in the first intron of the BCSG1 gene. Mutation of either AP1 motif on the BCSG1 promoter constructs markedly reduces the promoter activity. We further show that 12- O -tetradecanoylphorbol-13-acetate (TPA) increases ...