Fra-1 regulates gene expression involved in various processes such as cell growth and cell death and regulates the expression of genes controlling tissue/cell remodeling, such as MMP-1, MMP-2, and MMP-9, mainly at the transcriptional level [7–11]. We have recently shown that Fra-1-...
Gene ID (NCBI)317 RRIDAB_10859252 ConjugateUnconjugated FormLiquid Purification MethodAntigen affinity purification Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage ConditionsStore at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.20...
Synonyms CARD7, CLR17.1, DEFCAP, DEFCAP L/S, KIAA0926, NAC, NALP1, NLRP1, PP1044, SLEV1, VAMAS1 Calculated Molecular Weight 1473 aa, 166 kDa GenBank Accession Number BC051787 Gene Symbol NLRP1 Gene ID (NCBI) 22861 RRID AB_2879728 Conjugate Unconjugated Form Liquid Purification Method...
Although the cytotoxin process of vacuolization has been studied profusely in vitro and in vivo, the innate immune response initiated by the toxin has been usually studied in murine models of infection, using knockout mutants deleting the hlyA gene (encoding the monomeric toxin). In efforts to ...
3.2. Targeting the FOSL1 Gene and Fra-1 mRNA The drawbacks of global AP-1 inhibition highlight the importance of developing Fra-1-specific drugs, which should represent better therapeutic bullets. FOSL1 expression can be inhibited in cancer cells by several strategies, either irreversibly by gene...
QIAGEN 9002008 Rotor-Gene Q MDx 2plex, Priority QIAGEN 971460 therascreen® KRAS Pyro Kit (24) CE QIAGEN 292043 mericon Turkey (24) QIAGEN 133207 NeXtalStock K/Na tartrate (200) QIAGEN 292073 mericon Ruminant Kit (24) QIAGEN 929104 QIAxcel RNA QC Kit v2.0 (1200) ...
Gene Symbol APAF1 Gene ID (NCBI) 317 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1%...
a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility...
At the gene level, 10 genes from the STG that were consistently differentially expressed in this study and in the MSBB study (one of the three cohorts within the AMP-AD initiative) were enriched in microglial genes (TREM2, C3AR1, ITGAX, OLR1, CD74, and HLA-DRA), but also included ...
BioGPS and MyGene.info: organizing online, gene-centric information Nucleic Acids Res, 41 (2013), pp. D561-D565 Google Scholar 48 E.J. Jansen, G.J. Martens Novel insights into V-ATPase functioning: distinct roles for its accessory subunits ATP6AP1/Ac45 and ATP6AP2/(pro) renin receptor...