The results from the analysis of know targets imply that the characteristics of motif distribution in the promoter regions will give some clues for target prediction. In addition, Gene ontology annotation information is introduced in the determining of the candidate target genes following the hypothesis...
Progression and prognosis of HBV-related HCC correlates with the expression of the cytokine osteopontin (Opn), an established AP-1 target gene. Opn expression was strongly reduced in HBV+ livers and primary mouse hepatocytes lacking c-Jun, demonstrating that c-Jun regulates hepatic Opn expression ...
JUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein(Jun proto-oncogene, AP-1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronles...
这个基因是无内含子的,被定位到1P32-P31,一个涉及人类恶性肿瘤易位和缺失的染色体区域。This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to ...
AP-1 might be a good target for anticancer therapy. Abstract The AP-1 transcription factor is a dimeric complex that contains members of the JUN, FOS, ATF and MAF protein families. AP-1 proteins are primarily considered to be oncogenic, but recent studies have challenged this view — some ...
Expression of c-Jun, a target gene of Jun/AP-1, increases through JNK-induced transactivation. JNK, p38 and ERK can upregulate transcriptional activation of c-Fos, via phosphorylation and activation of ETS domain transcription factor (ELK-1). c-Jun and c-Fos form a dimer known as the...
Among these, JunD emerged as a self-regulated and IL-7 dependent gene (Fig. 5). Suppressive genes were generally involved in blocking inflamma- tory processes (Fig. 5). The cell line databases assessed for potential JunD target genes were also evaluated for functional ...
Gene ID (NCBI) 340061 RRID AB_10665370 偶联类型 Unconjugated 形式 Liquid 纯化方式 Antigen affinity purification UNIPROT ID Q86WV6 储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3. 储存条件 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20...
ENSEMBL Gene ID ENSG00000261371 RRID AB_2299349 偶联类型 Unconjugated 形式 Liquid 纯化方式 Antigen affinity purification UNIPROT ID P16284 储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3. 储存条件 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for...
LDL receptor gene transcription is selectively induced by t10c12-CLA but not by c9t11-CLA in the human hepatoma cell line HepG2 2006, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Show abstract Effects of fish oil and conjugated linoleic acids on expression of target g...