AP-1 family transcription factors: a diverse family of proteins that regulate varied cellular activities in classical hodgkin lymphoma and ALK+ ALCLActivator protein-1LymphomaCD30HodgkinALK+ ALCLClassical Hodgkin lymphoma (cHL) and anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (...
AP-1 family transcription factor is a dimeric protein complex composed of heterodimers between Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra-1, and Fra-2), and ATF family gene products. From:Differentiation,2011 About this page ...
Stress and the AP-1 family transcription factors AP-1 transcription factorsrepresent another family of proteins that regulate gene expression. The primary mechanism for regulation of these proteins is via induction of gene expression. The AP-1 proteins bind to the AP-1 promoter element, which ...
In addition, AP-1 family of proteins are important to maintain the basal expression of several genes31. AP-1 is a highly conserved transcription factor across wide range of organisms32,33,34. Recent studies have reported roles for vertebrate AP-1 in host-pathogen interactions including a role ...
5a,b). Next, we tested whether the histones at the AP-1 family target gene sequences are hyperacetylated in PD-1-deficient ITK–SYK-expressing T cells by performing GSEA using the H3K27ac ChIP–seq dataset (Fig. 4h; ChIP-Enrich analysis48) and the transcription factor target gene sets ...
The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1...
Interestingly, the crystal structure of MAF family members, bound to their respective DNA binding sites, revealed a unique bZIP structure that enables recognition of a long palindromic sequence referred to as the MAF recognition element (MARE) (Figure 1B) [8]. MARE I is an extension of TRE ...
别名:AP-1 complex subunit mu-1, AP-mu chain family member mu1A, Adaptor protein complex AP-1 mu-1 subunit, Adaptor-related protein complex 1 mu-1 subunit, Clathrin assembly protein 货号:FS-C6376 实验类型:夹心法 应用范围:血清、血浆、组织匀浆、细胞培养物上清或其它相关液体(本产品仅供实验室科...
Full Name solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 Synonyms xCT, SLC7A11, Cystine/glutamate transporter, CCBR1, Amino acid transport system xc- Calculated Molecular Weight 55 kDa Observed Molecular Weight 55 kDa, 35-40 kDa GenBank Accession Number BC01208...
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