Thus, family members are potentially exposed to cytotoxic drug residues from patients' excretions inside their homes. The study's aim was to evaluate the surface contamination and the potential uptake of antineoplastic drug residues by family members at home of chemotherapy patients. Overall, 265 ...
AntineoplasticPharmacokineticsDrug resistancePglycoproteinTaxaneTubulinBreast cancerEpothilonePurpose Ixabepilone, a semisynthetic analog of natural epothilone B, was ... FYF Lee,R Smykla,K Johnston,... - 《Cancer Chemotherapy & Pharmacology》 被引量: 237发表: 2009年 Preoperative chemotherapy treatment of ...
Drug Interaction Checker Pill Identifier Calculators Formulary Slideshow Baby Belly Aches: 7 Causes of Abdominal Pain in Pregnancy Overview Presentation DDx Workup Treatment Guidelines Medication Medication Summary Antineoplastics Chemotherapy modulating agent Show All Media Gallery Tables ReferencesReco...
关键词: Metformin Endometrial cancer Pten Mouse model of cancer Drug repurposing DOI: 10.1016/j.biopha.2023.115817 年份: 2023 收藏 引用 批量引用 报错 分享 全部来源 求助全文 dx.doi.org 相似文献The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of ...
5-Fluorouracil has antineoplastic activity and is a valuable drug especially for the treatment of tumors of the colon or rectum, but it has a wider application in cancer chemotherapy. Cytarabine, 4-amino-1-β-d-arabinofuranosylpyrimidin-2(1H)-one (cytosine arabinoside) is a valuable drug in ca...
drug resistance, tumor progression, and poor prognosis [7,8,9]. Alisertib shares the advantages of other mitotic kinase inhibitors over cytotoxic chemotherapy predecessors as it has minimal toxicity in non-proliferating tissues. However, the first randomized Phase III trial of alisertib (NCT01482962)...
Dosing device (400 cm2), where the syringe is fixed during the withdrawal of antineoplastic drug solutions from the vials and the injection into the infusion bags Surface area beneath the dosing device (400 cm2) Gripper of the robotic arm (180 cm2), which grasps the needed items during th...
Combination therapy involves the administration of two or more treatments with various mechanisms of action in order to overcome drug resistance and to reduce the effective dose of chemotherapy and thus the side effects. Consequently, combination therapy with a synergic effect would result in increased...
Alfaro, Guadalupe Delgado, Alfonso Cárabez, Brenda Anguiano and Carmen Aceves*AbstractBackground: Although mammary cancer (MC) is the most common malignant neoplasia in women, the mortalityfor this cancer has decreased principally because of early detection and the use of neoadjuvant chemotherapy. Of...
The human breast cancer cell line MCF-7 (ADR) which expresses a membrane bound glycoprotein (gp170) to confer multi-drug resistance (Leonessa et al., 1994) and its parental line MCF-7 p168 were used to assay the effects of cocoa fraction D & E. As shown in FIG. 19, the parental ...