Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat Genet 1994; 7: 13–21.Green LL, Hardy MC, Maynard-Currie CE, et al. Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat...
系统标签: antibodies cloning antigen cells sequencing memory ©2016NatureAmerica,Inc.Allrightsreserved.protocol1908|VOL.11NO.10|2016|natureprotocolsIntroDuctIonTheprotectivee icacyo humoralmemoryisprovidedbyatleasttwolayerso de ense.Antibodiesimmediatelybindtotheantigenandneutralizethepathogendirectlyand/ortrigger...
The design of clearing agents for antigen-specific antibodies presents several challenges: first, antigen-specific antibody levels are typically very low compared with those of antibodies of irrelevant specificities, and these two antibody pools are similar with shared constant regions but distinct ...
The presence of T cells specific for NY-ESO-1 antigen was not associated with the stage of disease, or to the presence or absence of NY-ESO-1 specific antibodies. We conclude that NY-ESO-1 is an immunogenic antigen in neuroblastoma patients and represents a candidate target for immune-...
关键词: Antigens Epitopes IgG Immunization Secondary Spleen Antibodies Monoclonal 抗原 表位 IGG 免疫接种 加强 脾 DOI: 10.4049/jimmunol.160.5.2051 被引量: 33 年份: 1998 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 掌桥科研 Semantic Scholar 万方医学 Semantic Scholar (全网免费下载) ...
Design Antibodies 5 design modes are available. Each mode corresponds to a config file in the configs/test folder: Config FileDescription codesign_single.yml Sample both the sequence and structure of one CDR. codesign_multicdrs.yml Sample both the sequence and structure of all the CDRs simultane...
Sustained high titers of neutralizing antibodies were elicited in three chimpanzees after sequential injections of different human immunodeficiency virus 1... Girard,M P,Kieny,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 606发表: 1991年 C-type...
To quantify the antigen-specific circulating IgG antibodies in immunized mice, 96 well ELISA plates were performed as previously reported [46,56] and with adaptations indicated in theSupplementary Material. Plates were analyzed in an ELISA reader at 450 nm and 560 nm (Multiskan Ex, Thermo Fisher...
Specific precipitable antibodies of both IgG and IgM classes were detected in sera of cattle naturally infected with B. besnoiti. The amount of specific antibodies of the IgG class precipitated by soluble antigen was in the range of 17-50 micrograms/ml serum while that of the IgM class ranged...
BACKGROUND:In liver transplantation (LT), preoperative desensitization therapy is considered necessary in patients positive for donor-specific anti-human leukocyte antigen antibodies (DSAs). However, the relationship between DSA intensity and the necessa