抗原提呈antigenpresentation抗原提呈是T细胞需要的T细胞识别抗原的方式有别于BCR及其抗体(识别线性抗原肽、MHC限制性)一些细胞能够摄取、加工、处理蛋白..
抗原提呈(antigenpresentation): 抗原肽-MHC复合物与T细胞接触过程中, 被T细胞识别,从而将抗原信息传递给 T细胞。 内源性抗原(endogenousantigen): 在抗原提呈细胞(APC)内新合成的抗原,如病毒抗原,肿瘤抗原等。 外源性抗原(exogenousantigen): 并非由APC合成,而来源于APC外的抗原。
Exogenous:producespeptides15aminoacidsorlongerforpresentationbyMHCclassIIPeptidebindsintoMHCpeptide-bindinggrooveProductionofCLIPfrominvariantchain(Ii)andsubsequentDM-mediatedreplacementofIiwithpeptideTheimmunoproteasomeEndogenouspeptideExogenouspeptideVCCVCCTheTCRantigen-combiningsiteTCRCDR3recognitionofpeptidepresentedbyMHC...
Antigen Processing and Presentation.ppt,上海交通大学医学院免疫学教研室 * 抗原加工提呈(Antigen Processing and Presentation) 张勇 T cells do not recognize native antigens Y Y B Y Y Y Y Y Y Y B Y T Y T Proliferation and antibody production No proli
论文 > 毕业论文 > Antigen presentation and leukocyte activation in the CNS:在中枢神经系统的抗原呈递和白细胞的活化 下载文档 收藏 打印 转格式 49阅读文档大小:3.35M10页亿百度文库上传于2015-01-09格式:PPT cns中枢神经系统肿瘤 NCCN 翻译 热度:
Key Concepts in Ag presentation between APCs & T cells 1. Most T cells recognize only peptides, whereas B cells can recognize peptides, lipids, nucleic acids,….etc. NK-T cells can recognize lipids. 2. T cells only recognize peptides displayed by MHC molecules on Ag-presenting cells (APC...
免疫学 7 APC and antigen presentation 抗原呈递细胞和抗原呈递 1 •B细胞受体或抗体识别多肽、蛋白、核酸、碳水化合物、脂质和小分子化合物 •大多数T细胞受体仅识别线性抗原肽(shortlinearpeptides)2 MHC结合并呈递抗原肽 3 T细胞受体识别线性抗原肽 4 抗原肽-MHCICD8T细胞抗原肽-MHCIICD4T细胞 5 6 不同类型...
presentation ability of macrophages stimulates proliferation of lymphocytes Summary Antigen is a ‘non-self subtance’ that can induce a specific immune response and react with the products of the immune response in vitro or in vivo. Antigen posses two properties: immunogenicity and im...
γδ T cells recognize intrinsic pathogenic molecules that are unlikely to mutate because they are not bound by the requirement of MHC-presentation. An example of this is the Mycobacterial cell wall component mycolylarabinogalactan-peptidoglycan (mAGP), which is recognized by bovine γδ T cells ...
chapter6 antigen processing and presentation to t lymphocytes 热度: Friction Stir Welding and Processing chapter11 热度: (数据库原理课件)Chapter11 Query Processing 热度: Tcellsdonotrecognisenativeantigens Y Y Y Y Y Y Y B Y T Y T Proliferationand ...