抗原提呈细胞 Antigen presenting Cells.ppt,抗原提呈细胞 (Antigen presenting Cells) 抗原呈递细胞(Antigen-presenting cell, APC):能够加工、处理抗原并将抗原信息提呈给T淋巴细胞的一类细胞,在机体的免疫识别、免疫应答与免疫调节中起重要作用。 专职性抗原呈递细胞
《医学免疫学》课程教学课件(PPT讲稿)抗原递呈细胞与抗原递呈 Antigen presenting cells and antigen presentation 团购合买资源类别:文库,文档格式:PPT,文档页数:48,文件大小:3.09MB 点击进入文档下载页(PPT格式) 共48页,可试读16页,点击继续阅读 ↓↓
T-cellsrecogniseproteinantigensthatare:a)Processedintopeptidesthen:b)PresentedbyMHCEndogenusAg (targetcell)ExogenousAgAPCpeptide→MHCITTumor/virusAPCpeptide→MHCIITAg→bacteriaCD8CD4I.Antigenpresentingcells(APC)Classification:ProfessionalAPC,non-professionalAPC,Targetcell...
抗原递呈细胞与抗原提呈antigenpresentingcellsandantigen 第15讲抗原提呈细胞与抗原提呈 AntigenPresentingCells&AntigenPresentation 武汉大学基础医学院免疫系熊洁 主要内容： 1、掌握抗原提呈细胞的概念、种类。2、熟悉抗原的处理和提呈的过程及抗原提呈机制。3、了解与抗原提呈作用相关的免疫分子及其在抗原递呈中的...
只有某些特定的细胞可以表达MHC I类和II类分子、协同刺激信号分子和各种粘附分子,这就是我们今天这期推送所要介绍的主角——抗原呈递细胞(Antigen-presenting cells, APC)。 ▉ 抗原呈递细胞 抗原呈递细胞(APC)的工作职责就是激活CTL和...
Antigen-presentingCells(APC)andAntigenPresentation免疫学系 T细胞受体如何识别抗原?T细胞受体类似于结合于细胞膜上的抗体Fab段 •B细胞受体或抗体识别多肽、蛋白、核酸、碳水化合物、脂质和小分子化合物•T细胞受体仅识别线性抗原肽(shortlinearpeptides)T细胞受体识别线性抗原肽 抗原肽-MHCICD8T细胞 抗原肽-MHCII...
presenting cells, which specialize in the presentation of antigens to T-cells. This process must occur so that the extracellular antigens can be recognized by theCD4 helper-T-cells.Monocytes– the largest of all leukocytes, these cells are able to differentiate into macrophages and myeloid-...
examplebyinhalation,ingestion,orinjection.Byendocytosisorphagocytosis,theseantigensaretakenintotheantigenpresentingcells(APCs)andprocessedintofragments.•Endogenousantigens Endogenousantigensareantigensthathave beengeneratedwithinthecell,asaresultof normalcellmetabolism,orbecauseofviral orintracellularbacterialinfection....
The immune response to dengue virus infection is a well-coordinated balancing act. New research shows that an imbalanced response — driven partially by the productive infection of antigen-presenting cells — is associated with progression to severe disease. ...
of Ag Cell surface peptides of Ag presented by cells that express MHC antigens Ag processing and presentation Since all cells expressing either class I or class II MHC molecules can present peptides to T cells, strictly speaking they all could be designated as Antigen Presenting Cells (APC)....