Antigen-presenting cells (APCs) are a heterogeneous group of immune cells that mediate the cellular immune response by processing and presenting antigens for recognition by certain lymphocytes such as T cells. Classical APCs include dendritic cells, macrophages, Langerhans cells and B cells. ...
Antigen presenting cells: Cells that capture antigens by endo- orphagocytosis, process them into small peptides, display them at theirsurfacethrough MHC molecules and provide co-stimulation signals that act synergistically to activate antigen-specificT cells.Antigen presenting cellsinclude B cells, macro...
Related to Antigen-presenting cells:perforin,Dendritic cells an·ti·gen (ăn′tĭ-jən)alsoan·ti·gene(-jēn′) n. A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a...
The meaning of ANTIGEN-PRESENTING CELL is any of various cells (such as a dendritic cell, macrophage, or B cell) that take up and process an antigen into a peptide fragment which when displayed at the cell surface in combination with a molecule of the ma
只有某些特定的细胞可以表达MHC I类和II类分子、协同刺激信号分子和各种粘附分子,这就是我们今天这期推送所要介绍的主角——抗原呈递细胞(Antigen-presenting cells, APC)。 ▉ 抗原呈递细胞 抗原呈递细胞(APC)的工作职责就是激活CTL和...
Choosing and preparing antigen-presenting cells. Curr. Protoc. Immunol. (Chapter 16, Unit 16.1).Harding CV (2001) Choosing and preparing antigen-presenting cells. Curr Protoc Immunol Chapter 16:Unit 16.1.:16.1.1–16.1.14Harding CV (2001) Choosing and preparing antigen-presenting cells . Curr ...
抗原提呈细胞 Antigen presenting Cells.ppt,抗原提呈细胞 (Antigen presenting Cells) 抗原呈递细胞(Antigen-presenting cell, APC):能够加工、处理抗原并将抗原信息提呈给T淋巴细胞的一类细胞,在机体的免疫识别、免疫应答与免疫调节中起重要作用。 专职性抗原呈递细胞
抗原递呈细胞与抗原提呈antigenpresentingcellsandantigen 第15讲抗原提呈细胞与抗原提呈 AntigenPresentingCells&AntigenPresentation 武汉大学基础医学院免疫系熊洁 主要内容: 1、掌握抗原提呈细胞的概念、种类。2、熟悉抗原的处理和提呈的过程及抗原提呈机制。3、了解与抗原提呈作用相关的免疫分子及其在抗原递呈中的...
Priming of T cells is a key event in vaccination, since it bears a decisive influence on the type and magnitude of the immune response. T-cell priming after mucosal immunization via the nasal route was studied by investigating the distribution of antigen-loaded antigen presenting cells (APCs) ...
The inherent tolerogenicity of the liver and its role in the regulation of innate and adaptive immunity are mediated by parenchymal and non-parenchymal antigen-presenting cells (APCs), cell-autonomous molecular pathways and locally produced factors. Here, we review the central role of liver APCs ...