antifactor Xa monitoringintermediate‐dose heparinvenous thromboembolismVTEStudy Objective. To describe unfractionated heparin (UFH) dosing requirements and monitoring parameters to achieve target antifactor Xa concentrations in pregnant women receiving intermediate-dose UFH therapy.Design. Retrospective cohort ...
To assess clinical outcomes in children treated with unfractionated heparin and monitored using an anti-factor Xa (Anti-FXa)-based nomogram. We also sought to assess the correlation between activated partial thromboplastin time (APTT) and Anti-FXa. This was a single-center, observational cohort ...
第一部分抗因子 Xa 活性测定前言低分子肝素(1ow molecular weight heparin,LMWH)与普通肝素(unfractionated hepafin,UFH)已广泛应用,目前血液透析中预防透析回路血栓形成,以低分子肝素 和普通肝素抗凝。其主要机制 LMWH 和 UFH 抑制抗 Xa 因子,使其与凝血酶及相互 作用达到止血的目的。目前发色底物法检测已经被认为...
Anti-factor Xa Microdialysis Microfluidic Real-time monitoring Therapeutic drug monitoring Abbreviations UFH unfractionated heparin LMWH low molecular weight heparin 1. Introduction Vascular thrombosis can occur in both arterial and venous circulation and is the leading cause of cardiovascular morbidity and mor...
Enoxaparin In patients with a moderate risk for DVT, enoxaparin is similar to unfractionated heparin in both efficacy and haemorrhagic profile, while preliminary ... S Noble,DH Peters,KL Goa - 《Drugs》 被引量: 65发表: 1995年 Factor Xa-activated whole blood clotting time (Xa-ACT) for bedsid...
Anti-XaactivityGeneralsurgeryHaemorrhageThrombosisA multicentre, double-blind, randomised trial was conducted to compare the efficacy of a low-molecular-weight (LMW) heparin, Logiparin, with that of an unfractionated (UF) heparin in the prophylactic treatment of thrombosis in patients undergo...
Interlaboratory agreement in the monitoring of unfractionated heparin using the anti-Cuker A, Ptashkin B, Konkle BA, et al. Interlaboratory agreement in the moni- toring of unfractionated heparin using the anti-factor Xa-correlated activated partial thromboplastin time. Thromb Haemostasis 2009;7:80-...
antifactor Xa monitoringintermediate-dose heparinpregnancyUFHunfractionated heparinvenous thromboembolismVTEStudy Objective. To describe unfractionated heparin (UFH) dosing requirements and monitoring parameters to achieve target antifactor Xa concentrations in pregnant women receiving intermediate-dose UFH therapy ...
Results Time to reach therapeutic level as well as total heparin dose required to reach this therapeutic level were much lower in the anti-Xa group when compared to aPTT group. Conclusion The use of anti-Xa-based protocol to monitor UFH infusion therapy resulted in better therapeutic control ...
Timely anticoagulation correlates with decreased PE‐associated mortality, but the ability to achieve a therapeutic activated partial thromboplastin time (aPTT) with unfractionated heparin (UFH) remains limited. Although some institutions have switched to a more accurate and reproducible test...