Anti‐factor Xa (anti‐Xa) monitoring of unfractionated heparin (UFH) is associated with less time to achieve therapeutic anticoagulation compared to the activated partial thromboplastin time (aPTT). However, it is unknown whether clinical outcomes differ between these methods of monitoring. The aim ...
This study assessed the relationships between rivaroxaban-specific anti-factor Xa activity (AXA) and unfractionated heparin (UFH)-specific AXA and determined the cutoff level for UFH-specific AXA in critical situations for patients undergoing rivaroxaban therapy. Methods Thirty-eight blood samples were ...
The Heparin Anti-Xa Therapeutic Range The current ACCP recommendations for monitoring unfractionated heparin therapy accommodate for the well-known problem of significant variability in aPTT reagent sensitivity. Unfortunately, the recommendations do not account for or discus... MA Smythe - 《Chest》 被引...
Although studies have shown that unfractionated heparin therapy is more strongly associated with anti-Xa activity, measurement of anti-Xa activity as a routine practice is not necessarily the standard of care due to lack of evidence1,2,3,4. Intensivists frequently have difficulty predicting ...
We aimed to identify attributing factors to the interindividual variabilities of the infusion rates in unfractionated heparin therapy. We included patients who required unfractionated heparin therapy to achieve the target APTT after cardiac surgery betwe
UFH levels (anti-Xa) varied between 0.3–2.1 IU/mL (median 0.8) and correlated with ACT-LR moderately (R2 = 0.73). The corresponding ACT-LR values were 146–337 s (median 214). ACT-LR and ACT measurements correlated only modestly with one another at this lower ...
Comparison of Monitoring Unfractionated Heparin Using Anti-Xa vs. aPTT in Patients With Ventricular Assist DevicesThe above picture is a graphical representation of the Hemoglobin (Hb) trend of our patient over a 5 month period. It has several troughs and peaks representing the Hb drop and blood...
Rosborough KT.Monitoring unfractionated heparin therapy with antifactor Ⅹa activity results in fewer monitoring tests and dosage changes than monitoring with the activated partial thromboplastin time[J].1999,19(06).Rosoborough TK. Monitoring unfractionated heparin therapy with antifactor Xa activity ...
What is known and objectivesThe two most common methods for monitoring unfractionated heparin (UFH) infusion are the activated partial thromboplastin time (aPTT) and the antifactor Xa heparin assay (anti-Xa). The purpose of this study is to compare the performance of an aPTT protocol vs. an ...
This study assessed the relationships between rivaroxaban-specific anti-factor Xa activity (AXA) and unfractionated heparin (UFH)-specific AXA and determined the cutoff level for UFH-specific AXA in critical situations for patients undergoing rivaroxaban therapy. Methods Thirty-eight blood samples were ...