Individual anticancer drugs continued 3- Alkylating agents A- Mechlorethamine B- Cyclophosphamide and ifosfamide C- Nitrosoureas Individual anticancer drugs continued 4- Microtubule inhibiters A- Vincristine and vinblastine Individual anticancer drugs continued 4- Steroid hormone and antagonists A- prednisolo...
anticancer drugsbioactive substanceApproaches to the standard presentation of the structural formulae of substances in the anticancer drug database of the Blokhin RCRC, RAMS have been described. These approaches provide the maximum appropriate use of the formulae in systems of biological activity ...
Adverse haematological complications of anticancer drugs. Clinical presentation, management and avoidance. Drug Safety 1993 ; 8 : 213-24.Bodensteiner DC, Doolitde Ge. Adverse haematological complications of anticancer drugs. Clinical presentation, management and avoidance. Drug Saf. 8:213-24, 1993....
This combined approach is able to improve the efficiency of standard cancer therapies by allowing for decreased chemotherapy doses, and neem extracts have also proved to be useful in reducing the toxicity of chemotherapy drugs. In conclusion, this review highlighted the effectiveness of A. indica ...
Current literature also indicates that lichen-derived compounds, as well as their synthetic derivatives, can enhance the effects of currently used anticancer drugs. For instance, the co-treatment of lobarstin, a secondary metabolite isolated from Stereocaulon alpinum, enhanced toxicity of temozolomide ...
The accumulation of antitumor drugs in tumors is enhanced, and the solubility, stability, and bioavailability problems often associated with these agents are avoided through the nanoformulation of drugs into liposomes [234]. The introduction of the liposomal drug-delivery method has had a profound ...
Table 2. Antiproliferative activity (IC50) of colchicine (1) and its derivatives (2–21) compared with antiproliferative activity of standard anticancer drugs doxorubicin and cisplatin and the calculated values of the resistance index (RI) of tested compounds. Table 3. Computational predictions of ...
However, in the past few decades, with the availability of resources and published literature, natural compounds have gained enormous attention for their ability to target chronic diseases like cancer uniquely; unlike synthetic drugs, which usually act on one or limited mechanisms, they can ...
Hyaluronic acid (HA), a main component of the extracellular matrix, is widely utilized to deliver anticancer drugs due to its biocompatibility, biodegradability, non-toxicity, non-immunogenicity and numerous modification sites, such as carboxyl and hydroxyl groups. Moreover, HA serves as a natural ...
More specifically, EVs can effectively embed and carry endogenous components, such as RNAs, peptides, and lipids, as well as exogenous drugs and viruses [17–19]. In response to the growing attention to exploring cancer vaccine, Dexo (EVs from DCs) was identified and its application ...