Among the identified biomarkers, circulating T cells are one of the most promising because of their indispensable contribution to anti-PD-(L)1 therapy. The present review aimed to thoroughly explore the potential of circulating T cells as biomarkers of anti-PD-(L)1 ther...
2024年9月19日,于君教授团队在Cancer Cell上发表了题为Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer的研究论文。该研究提示了,Fn丰度可能是预测微卫星稳定型结直肠癌中anti-PD-1治...
2021年12月23日,北京大学生物医学前沿创新中心(BIOPIC)、生命科学学院、北京未来基因诊断高精尖创新中心(ICG)张泽民课题组联合301医院韩为东课题组在国际期刊Nature Cancer上发表了题为Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted T cells during anti-PD-1 therapy in lung...
anti-PD-1 antibody. These unique features of Met@Man-MPs contribute to boost anti-PD-1 antibody therapy, improving anticancer efficacy and long-term memory immunity after combination treatment. Our results support Met@Man-MPs as a potential drug to improve tumor resistance to anti-PD-1 therapy....
2021年12月23日,北京大学生物医学前沿创新中心(BIOPIC)、生命科学学院、北京未来基因诊断高精尖创新中心(ICG)张泽民课题组联合301医院韩为东课题组在国际期刊Nature Cancer上发表了题为Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted T cells during anti-PD-1 therapy in lung...
forward the first anti-PD-1 therapy for advanced melanoma in China.” “The approval of our anti-PD-1 therapy reflects the Chinese government’s strong commitment to expedite the introduction of innovative therapies to Chinese patients,” said Joseph Romanelli, president of MSD ...
Peng-FeiZhang, Chao Gao, Xiao-Yong Huang, Jia-Cheng Lu, Xiao-Jun Guo, Guo-Ming Shi,Jia-Bin Cai, Ai-Wu Ke.Cancer Cell-Derived Exosomal circUHRF1 Induces Natural Killer Cell Exhaustion and May Cause Resistance to anti-PD1 Therapy in Hepatocellular Carcinoma.Molecular Cancer2020 Jun27;19(1...
Caroline Robert, MD, PhD, discusses the role of adjuvant anti–PD-1 therapy in resected stage IIB/IIC melanoma based on findings from the KEYNOTE-716 and CheckMate 76K trials. This is a modal window. The Playback API request failed for an ...
11. Abbas HA, Sun H, Pierce SR, Kanagal-Shamanna R, Li Z, Yilmaz M et al. Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy. Blood Adv. 2022 Apr:bloodadvances.2022007172. ...
“Importantly, Keytruda provides a foundation for the treatment of lung cancer in China and now more patients with non-small cell lung cancer may have the opportunity to benefit from combination therapy with Keytruda.” More than 787,000 cases of lung cancer are diagnosed in China every year, ...