Objectives: The aim of the current study was to describe the clinical spectrum and associations of anti-U1-RNP (+) patients. Methods: From the 25-year database of the immunology laboratory of the Department of Pathophysiology, those patients with ANA>1:320 and anti-U1RNP (+) were ...
Twenty-three had U1-(U1--ab). The clinical findings in U1--ab-positive patients were consistent with (MCTD). Disease was more serious in the U1--ab-positive patients in terms of severity as well as mortality due to . Thus, in this patient population, U1--ab positivity predicted an ...
Staining patterns of standard sera from the Autoantibody Standardization Committee (www.AutoAb.org). (A) IS2072 for anti-dsDNA gives homogeneous or AC-1 pattern that is expected the same for antihistone. IS2075 anti-U1RNP (B) and IS2076 anti-Sm (C) both give large/coarse speckled or AC...
Correlation analysis between anti-U1-snRNP, anti-Sm, and anti-VASP antibodies revealed only a non-significant positive correlation. Furthermore, the positivity rates of anti-RNP and anti-SM in anti-VASP+ NPSLE were both 62.5 %, while the positivity rates of anti-VASP in anti-RNP+ and anti...
临床意义 1、抗-HBe和抗-HBs不同,e抗体不是保护性抗体,不代表患者有了免疫力。有时检查出e抗体阳性,但肝细胞内仍然可以查出乙型肝炎病毒DNA,表明病毒仍然存在。 2、阳性提示病毒复制减少,传染性变弱。 3、表示HBV复制水平低[ 但有前C区/BCP(基本核心启动子)突变者例外]
Anti-La antibodies occur practically together with anti-SSA/Ro antibodies, but not vice versa as in the case of the relation between anti-Sm and anti-U1RNP... O Meyer - Springer Vienna 被引量: 5发表: 2009年 AB0817CLINICAL ASSOCIATION OF ANTI-RO52 ANTIBODIES IN SYSTEMIC SCLEROSIS: A SINGL...
A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen To test whether immunizing mice with autoantigens closely linked to mixed connective tissue disease (MCTD) could induce an MCTD-like clinical syndrome dist... EL Greidinger,YJ Zang,K Jaimes,... - ...
(B) Grobgranuläres nukleäres Muster: grobgranuläre Fluoreszenz der Interphasekerne bei Aussparung der Nukleoli; Chromatin der mitotischen Zellen negativ (U1-RNP-Antikörper eines MCTD-Patienten). (C) Pleomorphes Muster: pleomorphe nukleäre Fluoreszenz am Beispiel eines PCNA-...
MSA = myositis specific antibodies (Jo-1, PL-7, PL-12, OJ, EJ, Mi-2, SRP, TIF-1γ, MJ/NXP-2, SAE, MDA-5/CADM-140; MAA = myositis associated antibodies (Pm/Scl, Ku, U1RNP, U3RNP, Ro52). 3.4. Radiographic features of ARS-ILD Radiographic features of IIM and SSc associated...
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