The anti-U1RNP antibody was found in 13 of the 14 patients. There were no significant differences in cerebrospinal fluid findings between the drug-induced group and the non-drug-induced group. Conclusions: SLE or MCTD patients with aseptic meningitis tend to have anti-U1RNP antibody.Okada...
Both speckled antinuclear antibody (ANA) and anti-U1 ribonucleoprotein (RNP) antibody were positive, but anti-double-stranded DNA (dsDNA) antibody and anti-Smith (Sm) antibody were negative, while complement levels were normal. Renal biopsy revealed membranous glomerulonephritis (MGN) with diffuse ...
Anti-Nuclear Antibody (ANA) 4) Anti-RNP antibodies (Speckled or Nucleolar Pattern) a) Specifically for the differential diagnosis of: 1. Systemic rheumatic diseases 2. Follow-up analysis of collagen vascular disorders 5) Anti-SSA and Anti-SSB (Speckled Pattern) ...
抗着丝点抗体(anti-centromere antibody,ACA)由Moroi等于1980年发现,其主要识别着丝粒蛋白(centromere proteins,CENP),ACA识别的CENP主要有4种:CENP-A,CENP-B,CENP-C,CENP-D.
84 Anti-U11/U12 RNP antibodies have been reported in 3.2% of patients with SSc who had no other SSc-associated autoantibodies. The presence of anti-U11/U12 RNP antibodies was associated with pulmonary fibrosis (79% of antibody positive vs 37% of antibody negative) and a 2.25-fold greater...
1965年Walker等应用间接免疫荧光法(IIF),发现 PBC患者血清中存在抗线粒体抗体(anti-mitochondrial antibody,AMA)。其后研究发现,AMA是一种以线粒体为靶抗原、无种属和特异性的自身抗体。根据线粒体膜上能与AMA反应的9种自身抗原,将AMA分为9种亚型(Ml～M9),其中高滴度的抗M2型线粒体抗体是PBC的重要血清学指标,...
Similar to that observed in relation to lymphopenia, anti-Ro52/TRIM21 but not anti-SSA/Ro60 was found to be positively associated with Raynaud’s phenomenon. This relationship was independent of the presence of anti-U1RNP, an antibody known to be related to Raynaud’s phenomenon even in SLE...
Anti-RNA polymerase III antibody prevalence and associated clinical manifestations in a large series of French patients with systemic sclerosis: a cross-sectional study. J Rheumatol. 2010;37:125–30. Article CAS PubMed Google Scholar Petri MH, Satoh M, Martin-Marquez BT, Vargas-Ramirez R, ...
Histidyl-tRNA synthetase (Jo-1 antigen) 62 IPF Sensitivity: Antibody present in 68% of PF-AID (myositis) patients compared to 3% IPF alone and 7.5% myositis alone Bernstein et al. (1984) 19 PF-AID (myositis) 53 myositis alone Specificity: >99% normal and 98% autoimmune controls Topoi...
Conclusions: In SLE patients, increased serum IL-10 levels were associated with increased disease activity and risk of anti–SS-A/Ro antibody positivity. Keywords: systemic lupus erythematosus; IL-10; IL-6; anti-SS-A/Ro antibodies; disease activity; organ involvement...